Diethyl chlorophosphate

Diethyl chlorophosphate Basic information

Product Name:	Diethyl chlorophosphate
Synonyms:	Diethoxy chlorophosphate;Phosphoric acid chloride diethyl ester;Chloridophosphoric acid diethyl;Chloridophosphoric acid diethyl ester;Chlorophosphonic acid diethyl;Chlorophosphonic acid diethyl ester;Chlorophosphonic acid O,O-diethyl ester;Diethyl phosphoric chloride
CAS:	814-49-3
MF:	C4H10ClO3P
MW:	172.55
EINECS:	212-396-4
Product Categories:	Phosphorus compounds;Pharmaceutical Intermediates;Miscellaneous Reagents
Mol File:	814-49-3.mol

Diethyl chlorophosphate Chemical Properties

Melting point	95-96 °C
Boiling point	60 °C2 mm Hg(lit.)
density	1.194 g/mL at 25 °C(lit.)
vapor density	5.94 (vs air)
vapor pressure	0.1 mm Hg ( 25 °C)
refractive index	n20/D 1.416(lit.)
Fp	142 °F
storage temp.	2-8°C
solubility	Chloroform (Sparingly)
form	Liquid
color	Clear colorless to light yellow
Water Solubility	Soluble in alcohol and chloroform. Slightly soluble in water.
Sensitive	Moisture Sensitive
BRN	471433
Stability:	Hygroscopic, Moisture Sensitive
InChIKey	LGTLXDJOAJDFLR-UHFFFAOYSA-N
LogP	0.61
CAS DataBase Reference	814-49-3(CAS DataBase Reference)
NIST Chemistry Reference	Phosphorochloridic acid, diethyl ester(814-49-3)
EPA Substance Registry System	Diethyl chlorophosphate (814-49-3)

Safety Information

MSDS Information

Provider	Language
Phosphorochloridic acid diethyl ester	English
SigmaAldrich	English
ACROS	English

Diethyl chlorophosphate Usage And Synthesis

Chemical Properties	clear colorless to light yellow liquid
Uses	A phosphorous halide used for biochemical research. Also used as an intermediate in organic synthesis.
General Description	Clear liquid. Diethyl chlorophosphate is used as an intermediate in organic synthesis.
Reactivity Profile	Organophosphates, such as Diethyl chlorophosphate, are susceptible to formation of highly toxic and flammable phosphine gas in the presence of strong reducing agents such as hydrides. Partial oxidation by oxidizing agents may result in the release of toxic phosphorus oxides.
Health Hazard	Diethyl chlorophosphate is a cholinesterase inhibitor. It has high oral and very high dermal toxicity. It is a skin irritant. It is also toxic by inhalation.
Fire Hazard	Emits very toxic fumes of chloride and phosphorus oxides when heated to decomposition.
Safety Profile	Deadly poison by skin contact. Poison by ingestion. A cholinesterase inhibitor. See also PARATHION. Trace HCl catalyzes a hazardous reaction during the preparation of diethyl phosphate from diethyl chlorophosphate. When heated to decomposition it emits very toxic fumes of Cl and POx.

Diethyl chlorophosphate Preparation Products And Raw materials

Raw materials	Carbon tetrachloride-->Phosphorus trichloride-->Diethyl phosphite
Preparation Products	FOSTHIETAN-->TEPP-->PHORATE-OXON-->DEPBT-->1,1,3,3-TETRAMETHYL-1,3-DISILACYCLOBUTANE-->DIETHYL IODOMETHYLPHOSPHONATE-->Diethyl (trichloromethyl)phosphonate-->Ethylthiocyanate-->DIETHYL ALLYLPHOSPHONATE-->10-ethyl-10H-phenothiazine

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