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| | (-)-CAMPHOR Basic information | | Uses |
| | (-)-CAMPHOR Chemical Properties |
| Melting point | 177-179 °C(lit.) | | alpha | -44.8° (20/D)(EtOH) | | Boiling point | 204 °C(lit.) | | density | 0.990 | | vapor density | 5.24 (vs air) | | vapor pressure | 4 mm Hg ( 70 °C) | | refractive index | -44 ° (C=20, EtOH) | | Fp | 148 °F | | storage temp. | Sealed in dry,Room Temperature | | solubility | DMF: 30 mg/ml; DMSO: 20 mg/ml; Ethanol: 30 mg/ml; Ethanol:PBS (pH 7.2)(1:2): 0.33 mg/ml | | form | Adhering Crystals or Crystalline Powder | | Specific Gravity | 0.9853 (18℃) | | color | White to yellow | | Odor | at 10.00 % in dipropylene glycol. camphor | | Odor Type | camphoreous | | optical activity | [α]20/D 43°, c = 10 in ethanol | | explosive limit | 0.6-4.5%(V) | | Water Solubility | Soluble in water. (0.34 g/L) at 20°C | | Merck | 14,1732 | | BRN | 4291747 | | Stability: | Stable. Incompatible with strong reducing agents, strong oxidizing agents, chlorinated solvents. Protect from direct sunlight. | | InChIKey | DSSYKIVIOFKYAU-OIBJUYFYSA-N | | LogP | 2.089 (est) | | CAS DataBase Reference | 464-48-2(CAS DataBase Reference) | | EPA Substance Registry System | l-Camphor (464-48-2) |
| Hazard Codes | F,Xi | | Risk Statements | 11-36/37/38 | | Safety Statements | 16-26 | | RIDADR | UN 2717 4.1/PG 3 | | WGK Germany | 1 | | RTECS | EX1250000 | | Autoignition Temperature | 870 °F | | TSCA | Yes | | HazardClass | 4.1 | | PackingGroup | III | | HS Code | 29142910 |
| | (-)-CAMPHOR Usage And Synthesis |
| Uses | (1S,4S)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-one also known by its common name as (-)-Camphor is a chiral intermediate of camphor and is used as a flavour additive in foods and sweetners. | | Chemical Properties | white crystals | | Uses | (1S)-(-)-Camphor is used as chiral intermediate and chiral auxiliary precursor. It is used in the synthesis of high-potency sweeteners. It acts as catalytic agent and petrochemical additive. | | Definition | ChEBI: The S-enantiomer of camphor. | | General Description | Colorless or white crystals. Fragrant and penetrating odor. Slightly bitter and cooling taste. Odor index at 68°F: 40. Flash point 149°F. Burns with a bright, smoky flame. Sublimes appreciably at room temperature and pressure; 14% sublimes within 60 minutes at 176°F and 12 mm Hg. | | Air & Water Reactions | Flammable. Slightly water soluble. | | Reactivity Profile | (-)-CAMPHOR may be sensitive to heat and direct sunlight. Incompatible with strong oxidizing agents, strong reducing agents and chlorinated solvents. Also incompatible with potassium permanganate. Salts of any kind should not be added to (-)-CAMPHOR in water. Reacts violently with chromic anhydride . | | Fire Hazard | (-)-CAMPHOR is flammable. | | Purification Methods | Crystallise it from EtOH, 50% EtOH/water, MeOH, or pet ether or from glacial acetic acid by addition of water. It can be sublimed (50o/14mm) and also fractionally crystallised from its own melt. It is steam volatile. It should be stored in tight containers as it is appreciably volatile at room temperature. The solubility is 0.1% (H2O), 100% (EtOH), 173% (Et2O) and 300% |
| | (-)-CAMPHOR Preparation Products And Raw materials |
| Raw materials | Bicyclo[2.2.1]heptan-2-ol, 1,7,7-trimethyl-, (1S,4S)- (9CI)-->Bicyclo[2.2.1]heptane-2-thione, 1,7,7-trimethyl-, (1S,4S)--->(1S)-1,7,7-trimethylbicyclo[2.2.1]heptan-2-one oxime-->1,7,7-trimethylbicyclo[[]2.2.1]heptan-2-ol, exo-(±)-->L(-)-Borneol | | Preparation Products | Ethylbenzene-->(1S,E)-(-)-Camphorquinone 3-oxime |
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