Sodium chlorodifluoroacetate

Sodium chlorodifluoroacetate Basic information
Product Name:Sodium chlorodifluoroacetate
Synonyms:DIFLUOROCHLOROACETIC ACID SODIUM SALT;CHLORODIFLUOROACETIC ACID, NA;CHLORODIFLUOROACETIC ACID SODIUM;CHLORODIFLUOROACETIC ACID SODIUM SALT;chlorodifluoro-aceticacisodiumsalt;SODIUM CHLORODIFLUOROACETATE;Sodium chlorodifluoroacetate 97%;Sodiumchlorodifluoroacetate97%
CAS:1895-39-2
MF:C2H2ClF2NaO2
MW:154.47
EINECS:217-586-0
Product Categories:Miscellaneous Reagents;Pharmaceutical Intermediates;Fluorinated Building Blocks;Fluorinating Reagents & Building Blocks for Fluorinated Biochemical Compounds;Synthetic Organic Chemistry
Mol File:1895-39-2.mol
Sodium chlorodifluoroacetate Structure
Sodium chlorodifluoroacetate Chemical Properties
Melting point 196-198 °C (lit.)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility Soluble in dimethoxyethane, diglyme (0.60 g mL-1), triglyme, dimethyl formamide.
form Powder
color White to off-white
BRN 4162363
InChIKeyMRTAVLDNYYEJHK-UHFFFAOYSA-M
CAS DataBase Reference1895-39-2(CAS DataBase Reference)
EPA Substance Registry SystemAcetic acid, chlorodifluoro-, sodium salt (1895-39-2)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-37/39-24/25-36/37/39
WGK Germany 3
Hazard Note Irritant
TSCA T
HazardClass IRRITANT, HYGROSCOPIC
HS Code 29159080
MSDS Information
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Sodium chlorodifluoroacetate Usage And Synthesis
Chemical Propertieswhite to off-white powder
UsesIt is used as pharmaceutical intermediate. Reactions of aldehydes with triphenylphosphine and sodium chlorodifluoroacetate yield 1,1-difluoro olefins. It is a general reaction and a one step synthesis.
Sodium chlorodifluoroacetate Preparation Products And Raw materials
Preparation Products4-(DIFLUOROMETHOXY)-3-(CYCLOPROPYLMETHOXY)-BENZALDEHYDE-->METHYL CHLORODIFLUOROACETATE-->4-METHOXYPHENYL ISOCYANIDE-->4-Difluoromethoxy-3-hydroxybenzaldehyde-->[(difluoromethyl)thio]benzene-->4-DIFLUOROMETHOXY-3-METHOXY-BENZALDEHYDE-->(2-ISOCYANOETHYL)BENZENE-->2-(3-Methylphenyl)-1,3,4-oxadiazole-->4-broMo-2-(difluoroMethoxy)-6-Methylpyridine-->4-(DIFLUOROMETHOXY)-3,5-DIMETHOXYBENZALDEHYDE-->1-(difluoromethoxy)-2-methoxy-4-nitrobenzene-->1,3,4-Oxadiazole, 2-[1,1'-biphenyl]-4-yl--->1-chloro-2-(difluoromethoxy)-4-nitrobenzene-->1-Naphthalenol,formate(9CI)-->3-Bromo-4-difluoromethoxybenzaldehyde
Sodium benzoate Sodium acetate Sodium chloride Sodium bicarbonate Dichloroacetyl chloride Chlorodifluoroacetic acid SODIUM FLUOROACETATE Sodium chlorodifluoroacetate sodium Trisodium phosphate Diclofenac sodium Sodium citrate Sodium fluorosilicate Sodium hydroxide Trisodium hexafluoroaluminate Sodium chlorite 8-CHLOROADENOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE, RP-ISOMER SODIUM SALT Sodium chloroacetate

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