Desmethylanhydroicaritin

Desmethylanhydroicaritin Basic information

Product Name:	Desmethylanhydroicaritin
Synonyms:	Desmethylanhydroicaritin;3,4',5,7-Tetrahydroxy-8-(3-methyl-2-butenyl)flavone;8-Prenylkaempferol;Desmethylicaritin;Noranhydroicaritin;8-C-Prenylkaempferol;3,5,7-Trihydroxy-2-(4-hydroxyphenyl)-8-(3-Methyl-2-buten-1-yl)-4H-1-benzopyran-4-one;4'-DesMethylicaritin
CAS:	28610-31-3
MF:	C20H18O6
MW:	354.35
EINECS:
Product Categories:	Aromatics;Heterocycles;Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals
Mol File:	28610-31-3.mol

Desmethylanhydroicaritin Chemical Properties

Melting point	220-222°C
Boiling point	605.7±55.0 °C(Predicted)
density	1.444±0.06 g/cm3(Predicted)
storage temp.	Refrigerator
solubility	Acetone (Slightly), Methanol (Slightly)
form	Solid
pka	6.45±0.40(Predicted)
color	Light Yellow to Yellow
Stability:	Hygroscopic

Safety Information

MSDS Information

Desmethylanhydroicaritin Usage And Synthesis

Chemical Properties	Yellow Solid
Uses	A metabolite of Icariin. Icaritin and Desmethylicaritin, two metabolites of Icariin, dramatically inhibit the growth of most malignant cells. They also have significant antiangiogenesis properties, inhibiting or eliminating entirely the development of new malignant cells.
target	p38MAPK \| NF-kB \| PI3K \| NO \| NOS \| AP-1 \| JNK \| MEK \| ERK \| IkB \| IKK

Desmethylanhydroicaritin Preparation Products And Raw materials

Raw materials

2-Propen-1-one, 1-[2-hydroxy-4,6-bis(methoxymethoxy)phenyl]-3-[4-(methoxymethoxy)phenyl]--->Icaritin-->4-methoxymethoxy-benzaldehyde-->KaeMpferol Tri-O-MethoxyMethyl Ether-->5-O-(3-Methyl-2-butenyl) KaeMpferol Tri-O-MethoxyMethyl Ether-->DesMethyl Icaritin Tri-O-MethoxyMethyl Ether-->1-(2-hydroxy-4,6-bis(methoxymethoxy)phenyl)ethanone-->Kaempferol-->2',4',6'-Trihydroxyacetophenone monohydrate

Epimedin A Baohuoside V baohuoside I Epmedin B baohuoside II 3-[(6-Deoxy-3-O-beta-D-glucopyranosyl-alpha-L-mannopyranosyl)oxy]-7-(beta-D-glucopyranosyloxy)-5-hydroxy-2-(4-methoxyphenyl)-8-(3-methyl-2-buten-1-yl)-4H-1-benzopyran-4-one Sagittatosdie B Epmedin C baohuoside VII IKARISOSIDE F FLAVONE

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