ChemicalBook Product Catalog Pharmaceutical intermediates Bulk Drug Intermediates (R)-1-Boc-3-Hydroxypiperidine

(R)-1-Boc-3-Hydroxypiperidine

(R)-1-Boc-3-Hydroxypiperidine Basic information
Product Name:(R)-1-Boc-3-Hydroxypiperidine
Synonyms:(R)-1-Boc-3-hydroxypiperidine 95%;tert-Butyl (3R)-3-hydroxypiperidine-1-carboxylate, (3R)-1-(tert-Butoxycarbonyl)-3-hydroxypiperidine;tert- butyl (R)-3-hydroxy piperidine-1-carboxylate;(R)-1-Boc-3-hydroxypiperidine,97%;(R)-1-N-BOC-3-HYDROXYPIPERIDINE;(R)-1-BOC-3-PIPERIDINOL;(R)-1-BOC-3-HYDROXYPIPERIDINE;R-3-HYDROXY-1-(TERT-BUTOXYCARBONYL)PIPERIDINE
CAS:143900-43-0
MF:C10H19NO3
MW:201.26
EINECS:
Product Categories:Ibrutinib intermediate;Piperazine;Piperidine;Piperidines
Mol File:143900-43-0.mol
(R)-1-Boc-3-Hydroxypiperidine Structure
(R)-1-Boc-3-Hydroxypiperidine Chemical Properties
Melting point 43-50 °C
Boiling point 292.3±33.0 °C(Predicted)
density 1.107±0.06 g/cm3(Predicted)
Fp 104°C
storage temp. 2-8°C
solubility soluble in Methanol
pka14.74±0.20(Predicted)
form Low Melting Solid
color White to tan
optical activity[α]/D 22±3°, c = 5 in methanol
InChIKeyUIJXHKXIOCDSEB-MRVPVSSYSA-N
CAS DataBase Reference143900-43-0(CAS DataBase Reference)
Safety Information
Hazard Codes T
Risk Statements 36/37/38-41-37/38-25
Safety Statements 26-36/37/39-45
RIDADR UN 2811 6.1/PG 3
WGK Germany 3
HazardClass 6.1
PackingGroup Ⅲ
HS Code 29333990
MSDS Information
(R)-1-Boc-3-Hydroxypiperidine Usage And Synthesis
Chemical PropertiesWhite powder
Uses(R)-1-Boc-3-hydroxypiperidine has been used as a reactant for the synthesis of piperidinyl and pyrrolidinyl butyrates. It has also been used for the synthesis of constrained (-)-S-adenosyl-L-homocysteine (SAH) analogs as DNA methyltransferase inhibitors.
(R)-1-Boc-3-Hydroxypiperidine Preparation Products And Raw materials
Preparation Products(S)-3-Amino-1-N-Boc-piperidine-->(3R)-1-Boc-3-(4-aMino-3-iodo-1H-pyrazolo[3,4-d]pyriMidin-1-yl)piperidine
4,6-O-Benzylidene-N-Boc-1,5-imino-D-glucitol (R)-1-(TERT-BUTOXYCARBONYL)PIPERIDIN-3-YL METHANESULFONATE Carbonyl iron powder (R)-1-Boc-3-Hydroxypiperidine tert-Butanol tert-Butyl peroxyacetate Diethylene glycol monobutyl ether 1-Piperidinecarboxylic acid, 3-hydroxy-4-[4-(phenylmethoxy)phenyl]-, 1,1-dimethylethyl ester, trans- tert-Butyl (3R,4R)-4-(4-benzyloxyphenyl)-3-hydroxypiperidine-1-carboxylate BOC-BETA-HOMOHYP(BZL)-OH 4,6-O-BENZYLIDENE-N-(TERT-BUTOXYCARBONYL)-2-O-(4-TOLUENESULFONYL)-1,5-IMINO-D-GLUCITOL N-BOC-4-Hydroxypiperidine 3-Hydroxypiperidine (3S,4R)-4-AMINO-1-BOC-3-METHOXY-PIPERIDINE N-Boc-1,5-imino-1,5-dideoxy-D-glucitol TRANS-N-BOC-3-HYDROXY-4-PHENYL PIPERIDINE RESMETHRIN 2-Butoxyethanol
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