L-Pyroglutaminol

L-Pyroglutaminol Basic information

Product Name:	L-Pyroglutaminol
Synonyms:	(S)-(+)-5-Hydroxymethyl-2-pyrrolidinone,97%;(S)-5-Hydroxy-2-pyrrolidine;(S)-PyroglutaMinol;S)-5-(HydroxyMethyl)-2-pyrrolidinone/L-PyroglutaMinol;(S)-(+)-5-HydroxyMethyl-2-pyrrolidinone, 97% 1GR;L-pyroglutaMinol,(S)-(+)-5-HydroxyMethyl-2-pyrrolidinone;(S)-2-(HydroxyMethyl)pyrrolidin-5-one;(S)-5-(HydroxyMethyl)-2-pyrrolidone
CAS:	17342-08-4
MF:	C5H9NO2
MW:	115.13
EINECS:	605-678-7
Product Categories:	Heterocycles;Miscellaneous Reagents;pharmacetical;Amides (Chiral);Chiral Building Blocks;Synthetic Organic Chemistry;Pyrrolidine series;Heterocyclic Compounds
Mol File:	17342-08-4.mol

L-Pyroglutaminol Chemical Properties

Melting point	79-80 °C(lit.)
alpha	30 º (C=2, ETOH)
Boiling point	147-149°C 0,06mm
density	1.1808 (rough estimate)
refractive index	31 ° (C=5, EtOH)
Fp	147-149°C/0.06m
storage temp.	Inert atmosphere,Room Temperature
solubility	DMSO, Ethanol, Methanol
pka	14.35±0.10(Predicted)
form	Crystals or Crystalline Powder
color	White to light yellow
optical activity	[α]20/D +30°, c = 2 in ethanol
Water Solubility	Soluble in water.
BRN	4657914
CAS DataBase Reference	17342-08-4(CAS DataBase Reference)

Safety Information

Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-36-37/39
WGK Germany	3
F	3-10
HS Code	29051990

MSDS Information

Provider	Language
SigmaAldrich	English
ACROS	English
ALFA	English

L-Pyroglutaminol Usage And Synthesis

Chemical Properties	white to light yellow crystals or
Uses	(S)-Pyroglutaminol (cas# 17342-08-4) is a compound useful in organic synthesis.

L-Pyroglutaminol Preparation Products And Raw materials

Raw materials	Sodium hydroxide-->Ethyl acetate-->Methanol-->Dichloromethane-->Acetic acid-->Thionyl chloride-->Acetone-->Sodium bicarbonate-->Sodium borohydride-->Isopropyl alcohol-->L-Glutamic acid
Preparation Products	2-PyrrolidineMethanol, 4-hydroxy-, hydrochloride (1:1), (2S,4R)--->(S)-(+)-5-(Hydroxymethyl)-2-pyrrolidinone p-toluenesulfonate-->(+)-(3R,7aS)-Tetrahydro-3-phenyl-3H,5H-pyrrolo1,2-coxaole-5-one-->L-(+)-Glutamic acid hydrochloride-->(S)-5-(fluoromethyl)pyrrolidin-2-one

N-Methyl-2-pyrrolidone Polyglutamic acid N-Methyl-2-pyrrolidone Ketorolac tromethamine L-Pyroglutaminol N-Vinyl-2-pyrrolidone Polyvinylpyrrolidone L-Glutamic acid 2-Pyrrolidinone Dexketoprofen trometamol METHYL-2-PYRROLIDONE Hydroxymethyl GLDH Sodium L-pyroglutamate TRISTEARIN L-Pyroglutamic acid Z-PYR-OH Fosfomycin tromethamine

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