5,6-DIAMINO-2,4-DIHYDROXYPYRIMIDINE SULFATE

5,6-DIAMINO-2,4-DIHYDROXYPYRIMIDINE SULFATE Basic information
Product Name:5,6-DIAMINO-2,4-DIHYDROXYPYRIMIDINE SULFATE
Synonyms:4,5-DIAMINO-2,6-DIHYDROXYPYRIMIDINE SULFATE;4,5-DIAMINO-2,6-DIHYDROXYPYRIMIDINE SULPHATE;4,5-DIAMINO-2,6-DIHYDROXYPYRIMIDINE;4,5-DIAMINOURACIL SULFATE;5,6-DIAMINOURACIL SULFATE;5,6-DIAMINO-2,4-DIHYDROXYPYRIMIDINE;5,6-DIAMINO-2,4-DIHYDROXYPYRIMIDINE SULFATE;5,6-DIAMINO-2,4-DIHYDROXYPYRIMIDINE SULPHATE
CAS:32014-70-3
MF:C4H8N4O6S
MW:240.19
EINECS:250-899-0
Product Categories:Building Blocks;C4 to C5;Pyridines, Pyrimidines, Purines and Pteredines;Chemical Synthesis;Heterocyclic Building Blocks;Pyrimidines;Heterocyclic Compounds
Mol File:32014-70-3.mol
5,6-DIAMINO-2,4-DIHYDROXYPYRIMIDINE SULFATE Structure
5,6-DIAMINO-2,4-DIHYDROXYPYRIMIDINE SULFATE Chemical Properties
Melting point >260 °C (dec.)(lit.)
BRN 3781587
CAS DataBase Reference32014-70-3(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36
WGK Germany 3
RTECS YQ9625000
MSDS Information
ProviderLanguage
SigmaAldrich English
5,6-DIAMINO-2,4-DIHYDROXYPYRIMIDINE SULFATE Usage And Synthesis
Uses5,6-Diaminouracil sulfate is an intermediate in the synthesis of Paraxanthine (P192500) and Paraxanthine analogs.
Purification MethodsThe salt is quite insoluble in H2O but can be converted to the free base which is recrystallised from H2O and converted to the sulfate by addition of the required amount of H2SO4. The hydrochloride has m 300-305o(dec) and can be used to prepare the sulfate by addition of H2SO4; it is more soluble than the sulfate. The perchlorate has m 252-254o. The free base has max at 260nm (log 4.24) in 0.1M HCl. [Bogert & Davidson J Am Chem Soc 86 1668 1933, Bredereck et al. Chem Ber 86 850 1953, Sherman & Taylor Org Synth Coll Vol IV 247 1963, Barlin & Pfleiderer J Chem Soc (B) 1425 1971, Beilstein 25 II 382.]
5,6-DIAMINO-2,4-DIHYDROXYPYRIMIDINE SULFATE Preparation Products And Raw materials
Raw materialsSodium nitrite-->Ammonium hydroxide-->Urea-->1,4-Dioxane-->Ethyl cyanoacetate-->Sodium dithionite
6-amino-5-[(4-methylbenzylidene)amino]-2,4-pyrimidinediol 9-METHYLURIC ACID 1,3-Dimethyluric acid 6-AMINO-5-NITROSO-1,2,3,4-TETRAHYDROPYRIMIDINE-2,4-DIONE LITHIUM ACID URATE TETRAMETHYLURIC ACID 7,9-dihydro-3,9-dimethyl-1H-purine-2,6,8(3H)-trione AMMONIUM BIURATE SPECS AC-907/25005129 5,6-DIAMINO-2,4-DIHYDROXYPYRIMIDINE SULFATE DIHYDRATE 1-METHYLURIC ACID 6-AMINO-1,3-DIMETHYL-5-NITROSOURACIL 4,5-Diaminouracil 3-METHYLURIC ACID 1,9-DIMETHYL-2,6,8-TRIHYDROXYPURINE 7-METHYLURIC ACID 3,7-DIMETHYL-2,6,8-TRIHYDROXYPURINE DISODIUM URATE

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