1-(4-chlorophenyl)-3-cyanoguanidine

1-(4-chlorophenyl)-3-cyanoguanidine Basic information
Product Name:1-(4-chlorophenyl)-3-cyanoguanidine
Synonyms:N-(4-Chlorophenyl)-N’-cyanoguanidine;4-CHLOROPHENYLCYANOGUANIDINE;1-(4-chlorophenyl)-3-cyanoguanidine;(4-chlorophenyl)-dicyanodiamide;P-CHLOROPHENYL-CYANOGUANIDINE;1-CYANO-3-(4-CHLOROPHENYL)-GUANIDINE;GUANIDINE, -(4-CHLOROPHENYL)-N''-CYANO;1-(p-Chlorophenyl)-3-cyanoguanidine
CAS:1482-62-8
MF:C8H7ClN4
MW:194.62
EINECS:216-043-5
Product Categories:Amines;Aromatics;Benzene series;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File:1482-62-8.mol
1-(4-chlorophenyl)-3-cyanoguanidine Structure
1-(4-chlorophenyl)-3-cyanoguanidine Chemical Properties
Melting point 202-204 °C
Boiling point 279.0±42.0 °C(Predicted)
density 1.34±0.1 g/cm3(Predicted)
storage temp. Refrigerator
solubility DMSO (Slightly), Methanol (Slightly)
pka4.92±0.10(Predicted)
form Solid
color White
Safety Information
WGK Germany 3
HS Code 2926900005
MSDS Information
1-(4-chlorophenyl)-3-cyanoguanidine Usage And Synthesis
Uses1-(4-chlorophenyl)-3-cyanoguanidine used in the preparation of antimalarial agents.
UsesHalo-aryl substituted guanidine derivative used in the preparation of antimalarial agents. Proguanil USP Related Compound E (1-(4-chlorophenyl)-3-cyanoguanidine).
Synthesis Reference(s)The Journal of Organic Chemistry, 24, p. 1809, 1959 DOI: 10.1021/jo01093a619
1-(4-chlorophenyl)-3-cyanoguanidine Preparation Products And Raw materials
1-Cyano-3-isopropylguanidine Proguanil Related Compound C (25 mg) (1,5-bis(4-chlorophenyl)biguanide hydrochloride) 1-(3,4-dichlorophenyl)-5-isopropylbiguanide monohydrochloride 1-(3-Chlorophenyl)-5-isopropylbiguanide Hydrochloride Dicyandiamide 1-(4-chlorophenyl)-3-cyanoguanidine

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