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Methyl L-pyroglutamate

Methyl L-pyroglutamate Basic information
Product Name:Methyl L-pyroglutamate
Synonyms:2-PYRROLIDONE-5-CARBOXYLIC ACID METHYL ESTER;METHYL L-PYROGLUTAMATE;METHYL (S)-2-PYRROLIDINONE-5-CARBOXYLATE;METHYL (S)-(+)-2-PYRROLIDONE-5-CARBOXYLATE;L-PYR-OME;(+)-L-PYROGLUTAMIC ACID METHYL ESTER;L-PYROGLUTAMIC ACID METHYL ESTER;H-PGLU-OME
CAS:4931-66-2
MF:C6H9NO3
MW:143.14
EINECS:225-567-3
Product Categories:Chiral Reagents;Amino Acids;Amino Acid Derivatives;pharmacetical
Mol File:4931-66-2.mol
Methyl L-pyroglutamate Structure
Methyl L-pyroglutamate Chemical Properties
alpha 10.5 º (c=1, EtOH)
Boiling point 90°C (0.3 mmHg)
density 1.226
refractive index 1.486
Fp >110°C
storage temp. Inert atmosphere,Room Temperature
solubility Chloroform (Slightly), Ethanol (Sparingly)
form Liquid
pka14.65±0.40(Predicted)
color Pale yellow
optical activity[α]20/D +10.5°, c = 1 in ethanol
CAS DataBase Reference4931-66-2(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36
WGK Germany 3
HS Code 29337900
MSDS Information
Methyl L-pyroglutamate Usage And Synthesis
Chemical PropertiesBrown Oil
UsesMethyl (S)-Pyroglutamate (cas# 4931-66-2) is a compound useful in organic synthesis.
Methyl L-pyroglutamate Preparation Products And Raw materials
Preparation Products(S)-(+)-5-(Hydroxymethyl)-2-pyrrolidinone p-toluenesulfonate-->L-Pyroglutamamide-->(+)-(3R,7aS)-Tetrahydro-3-phenyl-3H,5H-pyrrolo1,2-coxaole-5-one-->AT-406-->L-(+)-Glutamic acid hydrochloride-->2-Pyrrolidinone,5-(3-methyl-5-isoxazolyl)-,(S)-(9CI)
Methyl DIRHODIUM (II) TETRAKIS(METHYL 2-PYRROLIDONE-5(S)-CARBOXYLATE)ACETONITRILE/2-PROPANOL COMPLEX N-OCTYL L-2-PYRROLIDONE-5-CARBOXYLATE METHYL DL-PYROGLUTAMATE Methyl L-pyroglutamate ALPHA-PYRIDOIN METHYL (S)-PYROGLUTAMATE DEANOL PIDOLATE Kresoxim-methyl Ethyl L-pyroglutamate GLDH Thiophanate-methyl Boc-L-Pyroglutamic acid methyl ester Z-PYR-ONP (S)-N-ALPHA-T-BUTYLOXYCARBONYL-PYROGLUTAMIC ACID T-BUTYL ESTER LABOTEST-BB LT00847896 L-Pyroglutamic acid METHYL THIOPHENE-2-CARBOXYLATE
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