ChemicalBook Product Catalog Pharmaceutical intermediates Heterocyclic compound Pyrimidines Dihydroxypyrimidine 2-Hydroxypyrimidine

2-Hydroxypyrimidine

2-Hydroxypyrimidine Basic information
Product Name:2-Hydroxypyrimidine
Synonyms:Pyrimidin-2(5H)-one;2-HYDROXYPYRIMIDINE;2-OXOPYRIMIDINE;PYRIMIDIN-2-OL;TIMTEC-BB SBB004380;2(1h)-pyrimidinone;2-Pyrimidinol;1H-pyrimidin-2-one
CAS:557-01-7
MF:C4H4N2O
MW:96.09
EINECS:209-149-8
Product Categories:PYRIMIDINE;alcohol
Mol File:557-01-7.mol
2-Hydroxypyrimidine Structure
2-Hydroxypyrimidine Chemical Properties
Melting point 177-178 °C(Solv: ethyl acetate (141-78-6))
density 1.28±0.1 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
pkapK1:2.24(＋1);pK2:9.17(0) (25°C)
CAS DataBase Reference557-01-7(CAS DataBase Reference)
NIST Chemistry Reference2(1H)-Pyrimidinone(557-01-7)
EPA Substance Registry System2(1H)-Pyrimidinone (557-01-7)
Safety Information
Hazard Codes Xn
Risk Statements 36/37/38-40
Safety Statements 22-26-36
MSDS Information
2-Hydroxypyrimidine Usage And Synthesis
UsesPyrimidin-2(5H)-one is a useful research chemical compound used in the preparation . of a palladium-containing metal-organic framework as a reusable catalyst for the Suzuki coupling of p-bromoanisole and phenylboronic acid.
DefinitionChEBI: Pyrimidin-2-ol is the hydroxypyrimidine that is pyrimidine mono-substituted at C-2 by a hydroxy group. It has a role as a Lewis base and an electron donor.
Purification MethodsIt crystallises from EtOH or ethyl acetate. Its solubility in H2O at 20o is 1g/2.2mL. [Albert J Chem Soc 4219 1952, Beilstein 24 III/IV 194.]. 2-Hydroxypyrimidine hydrochloride [38353-09-2] M 132.5, has m 203-205.5o(dec)
2-Hydroxypyrimidine Preparation Products And Raw materials
Raw materialsPolycarbodiiMide-->Purine
CYTIDINE 3'-MONOPHOSPHATE N4-Acetylcytidine 5-METHYLCYTIDINE Hydroxyapatite 2-Hydroxypyrimidine Hydroxy silicone oil Sulfadiazine Silver sulfadiazine 4-HYDROXYPYRIMIDINE 98% (+)-3',5'-O-(1,1,3,3-Tetraisopropyl-1,3-disiloxanediyl)cytidine 2-HYDROXYPYRIMIDINE HYDROCHLORIDE 99% 5'-O-Dimethoxytrityl-N-benzoyl-desoxycytidine 2-ISOPROPYL-6-METHYL-4-PYRIMIDINOL CYTOSINE BETA-D-ARABINOFURANOSIDE HYDROCHLORIDE 2'-Deoxycytidine hydrochloride Glycolic acid 5-Hydroxypyrimidine Camptothecin Series--10-hydroxycamptothecin
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