2,4-Dimethoxyacetophenone

2,4-Dimethoxyacetophenone Basic information

Product Name:	2,4-Dimethoxyacetophenone
Synonyms:	2',4'-DIMETHOXYACETOPHENONE;2,4-DIMETHOXYACETOPHENONE;2,4'-Dimethoxyacetaphenone;2',4'-Dimethoxyacethophenone, 98%;1-Acetyl-2,4-dimethoxybenzene;2',4'-Dimethoxyacetophenone,98%;AKOS BBS-00004235;1-(2,4-Dimethoxy-phenyl)-ethanone
CAS:	829-20-9
MF:	C10H12O3
MW:	180.2
EINECS:	212-587-2
Product Categories:	Building Blocks;C10;Carbonyl Compounds;Chemical Synthesis;Ketones;Organic Building Blocks;Aromatic Acetophenones & Derivatives (substituted);Acetophenone series;829-20-9
Mol File:	829-20-9.mol

2,4-Dimethoxyacetophenone Chemical Properties

Melting point	37-40 °C(lit.)
Boiling point	288 °C(lit.)
density	1.1272 (rough estimate)
refractive index	1.5430 (estimate)
Fp	>230 °F
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
solubility	soluble in Dichloromethane, Ethyl Acetate, Methanol
form	Crystalline Powder
color	White to off-white
Sensitive	Light Sensitive
BRN	511947
CAS DataBase Reference	829-20-9(CAS DataBase Reference)
NIST Chemistry Reference	2',4'-Dimethoxyacetophenone(829-20-9)

Safety Information

Hazard Codes	Xi
Safety Statements	24/25
WGK Germany	3
HazardClass	IRRITANT
HS Code	29145090

MSDS Information

Provider	Language
ACROS	English
SigmaAldrich	English
ALFA	English

2,4-Dimethoxyacetophenone Usage And Synthesis

Chemical Properties	white to off-white crystalline powder
Uses	2',4'-Dimethoxyacetophenone-d6 is an by-product in the synthesis of Paeonol-d3 (P133842). Paeonol-d3 is a labelled analogue of Paeonol (P133840), acting as a b-Secretase inhibitor an anti-apoptotic agent is used in the treatment of memory loss after ischemic stroke. Anti-inflammatory and analgesic.
Preparation	Obtained by reaction of dimethyl sulfate with resacetophenone in the presence of 10% aqueous sodium hydroxide (61%).
Definition	ChEBI: 2,4-Dimethoxyacetophenone is an aromatic ketone.

2,4-Dimethoxyacetophenone Preparation Products And Raw materials

Raw materials	N-cyclohexylacetamide-->Acetyl chloride-->2,4-Dimethoxybenzoic acid-->Acetonitrile-->Dimethyl sulfate-->Iodomethane-->Acetovanillone-->2,4-Dihydroxyacetophenone-->Acetic anhydride-->Dimethoxybenzene
Preparation Products	1-Chloro-2,4-dimethoxybenzene-->2,4-Dimethoxyphenylacetic acid-->2',6'-Dimethoxyacetophenone-->(2E)-1-(2,4-Dimethoxyphenyl)-3-(2-methoxyphenyl)prop-2-en-1-one

4'-Methoxyacetophenone Diphenyldimethoxysilane 2,6-Dimethoxybenzaldehyde 2,4-Dimethoxyacetophenone Dimethyldimethoxysilane 2'-Methoxyacetophenone 2',4'-Dichloroacetophenone 3,4-Dimethoxyacetophenone Rotenone 1,1-Dimethoxyethane 2',4-DIHYDROXY-4',6'-DIMETHOXYCHALCONE 6,7-DIMETHOXY-2,2-DIMETHYL-4-CHLOROMANONE RHOIFOLIN 3-Methoxyacetophenone Dimethoxymethane PIPERACETAZINE (250 MG) 3',5'-DIMETHOXYACETOPHENONE,3,5-DIMETHOXYACETOPHENONE,3',5'-Dimethoxyacetophenone 3,5-Dimethoxyacetophenone 1,2,3,4-TETRAMETHOXY-10-METHYLACRIDONE

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