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| | Agnuside Basic information |
| Product Name: | Agnuside | | Synonyms: | chasteberry oil;[(1r,2s,6s,7s)-7-hydroxy-2-[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3-oxabicyclo[4.3.0]nona-4,8-dien-9-yl]methyl 4-hydroxybenzoate;AGNUSIDE;AGNUSIDE WITH HPLC;AGNUSIDE(P);Agnuside (25 mg);Vitex negundo oil，Agnuside;OLEUMVITICISNEGUNDO Oil | | CAS: | 11027-63-7 | | MF: | C22H26O11 | | MW: | 466.44 | | EINECS: | | | Product Categories: | Aromatic Phenols | | Mol File: | 11027-63-7.mol |  |
| | Agnuside Chemical Properties |
| Melting point | 146℃ | | Boiling point | 785.5±60.0 °C(Predicted) | | density | 1.59±0.1 g/cm3(Predicted) | | storage temp. | -20°C | | solubility | DMSO, Methanol | | pka | 8.14±0.15(Predicted) | | form | neat | | color | Yellow | | optical activity | [α]/D -98.0±5°, c = 0.1 in ethanol | | BRN | 4925795 | | InChIKey | GLACGTLACKLUJX-QNAXTHAFSA-N | | LogP | -1.240 (est) |
| Hazard Codes | Xi | | Risk Statements | 36 | | Safety Statements | 26 | | WGK Germany | 3 | | HS Code | 29329990 |
| | Agnuside Usage And Synthesis |
| Chemical Properties | Yellow Oil | | Uses | Agnuside is an known iridoid glycoside found in Vitex herbs or plants. Agnuside have been used in various applications including in the treatment of premenstrual syndrome and regulation of menopause s
ymptoms. This is mainly due to the fact that Agnuside exhibits estrogen-like activities as it interacts with estrogen receptors (ER-alpha) and estrogen receptor-regulated pregesterone receptors. Recen
t studies have also evaluated Agnuside for the probable mechanism of anti-arthritic activity, which suggested the possible development of Agnuside as a therapeutic agent in the treatment of arthritis
by the modulation of the host immune response. | | Definition | ChEBI: Agnuside is a benzoate ester resulting from the formal condensation of the carboxy group of 4-hydroxybenzoic acid with the primary hydroxy group of aucubin. It is an iridoid glycoside found in several Vitex plants including Vitex agnus-castus. It has a role as a plant metabolite, an anti-inflammatory agent, a pro-angiogenic agent and a cyclooxygenase 2 inhibitor. It is a terpene glycoside, an iridoid monoterpenoid, a benzoate ester, a member of phenols, a beta-D-glucoside, a cyclopentapyran and a monosaccharide derivative. It is functionally related to an aucubin. |
| | Agnuside Preparation Products And Raw materials |
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