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| | 2-acetamido-3-methyl-3-(nitrososulfanyl)butanoic acid Basic information |
| Product Name: | 2-acetamido-3-methyl-3-(nitrososulfanyl)butanoic acid | | Synonyms: | N-(ACETYLOXY)-3-NITROSOTHIOVALINE;SNAP;(+/-)-S-NITROSO-N-ACETYLPENICILLAMINE;S-NITROSO-N-ACETYL-D,L-PENICILLAMINE;S-Nitroso-N-acetyl-DL-penicillamine,N-Acetyl-3-(nitrosothio)-DL-valine, S-Nitroso-N-acetylpenicillamine, SNAP;(R)-2-acetaMido-3-Methyl-3-(nitrosothio)butanoic acid;SNAP [S-Nitroso-N-acetylpenicillaMine];Anti-SNAP25, C-Terminal antibody produced in rabbit | | CAS: | 67776-06-1 | | MF: | C7H12N2O4S | | MW: | 220.25 | | EINECS: | | | Product Categories: | Signalling | | Mol File: | 67776-06-1.mol |  |
| | 2-acetamido-3-methyl-3-(nitrososulfanyl)butanoic acid Chemical Properties |
| Melting point | 150.5°C | | density | 1.4261 (rough estimate) | | refractive index | 1.5400 (estimate) | | RTECS | YV9383000 | | storage temp. | -20°C | | solubility | H2O: ≥2 mg/mL | | pka | 3.06±0.10(Predicted) | | form | powder | | color | green | | CAS DataBase Reference | 67776-06-1(CAS DataBase Reference) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36 | | WGK Germany | 3 |
| | 2-acetamido-3-methyl-3-(nitrososulfanyl)butanoic acid Usage And Synthesis |
| Description | SNAP is an S-nitrosothiol which serves as a NO donor and a potent vasodilator. Its stability in solution varies from seconds to hours depending on temperature, buffer composition and metal content. At pH 6-8 and 37°C, the half-life of SNAP is approximately six hours in the presence of transition metal ion chelators. | | Chemical Properties | 2-acetamido-3-methyl-3-(nitrososulfanyl)butanoic acid is green crystalline solid
| | Uses | Produced concentration-related relaxations of mouse anococcygeus, in a range similar to that already found for NO and other nitrovasodilators. A potent relaxant of non-vascular smooth muscle. Serves as an NO donor. | | Biochem/physiol Actions | NO donor; vasodilator, smooth muscle relaxant, lymphocyte activator. Activates soluble guanylyl cyclase. |
| | 2-acetamido-3-methyl-3-(nitrososulfanyl)butanoic acid Preparation Products And Raw materials |
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