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| | DPX-T5648 Basic information |
| | DPX-T5648 Chemical Properties |
| Hazard Codes | N | | Risk Statements | 50 | | Safety Statements | 61 | | RIDADR | UN3077 9/PG 3 | | WGK Germany | 2 | | RTECS | DG9096550 | | Hazardous Substances Data | 74222-97-2(Hazardous Substances Data) | | Toxicity | LD50 in male, female rats (mg/kg): >5000, >5000 orally (Harding) |
| | DPX-T5648 Usage And Synthesis |
| Uses | Herbicide. | | Definition | ChEBI: A benzoate ester that is the methyl ester of 2-{[(4,6-dimethylpyrimidin-2-yl)carbamoyl]sulfamoyl}benzoic acid. | | Agricultural Uses | Herbicide: Used to control annual and perennial grasses and broadleaf
weeds on landscapes, rights-of-ways, fence rows, forests,
industrial structure areas and non-crop land. Not listed for use
in EU countries. Registered for use in the U.S. | | Trade name | DPX-T5648®; KNOCKOUT®;
LANDMARK® MP (sulfometuron-methyl + chlorsulfuron);
OUST®; OUSTAR®; RIVERDALE®; STAMPRO® | | Environmental Fate | Soil. In unsterilized soils, 58% of 14C-labeled sulfometuron-methyl degraded after 24
weeks. Metabolites identified were 2,3-dihydro-3-oxobenzisosulfonazole (saccharin),
methyl-2-(aminosulfonyl)benzoate, 2-aminosulfonyl benzoic acid, 2-(((aminocarbonyl)amino)sulfonyl)benzoate and [14C]carbon dioxide. The rate of degradation in aerobic
soils was primarily dependent upon pH and soil type (Anderson and Dulka, 1985). The
reported half-life in soil was approximately 4 weeks (Hartley and Kidd, 1987).
Chemical/Physical. Sulfometuron-methyl is stable in water at pH values of 7 to 9 but
is rapidly hydrolyzed at pH 5.0 forming methyl 2-(aminosulfonyl)benzoate and saccharin.
When sulfometuron-methyl in an aqueous solution was exposed to UV light (λ = 300–400
nm), it degraded to the intermediate methyl benzoate which then mineralized to carbon
dioxide (Harvey et al., 1985). The hydrolysis half-lives of metsulfuron-methyl at pH 5
and 25 and 45°C were 33 and 2.1 days, respectively. At pH 7 and 45°C, the hydrolysis
half-life is 33 days (Beyer et al., 1988). | | Metabolic pathway | Sulfometuron methyl is relatively stable at neutral and
basic pH and undergoes cleavage of the sulfonylurea
linkage to yield methyl-2-(aminosulfonyl)benzoate and
4,6-dimethyl-2-aminopyrimidine as major hydrolysis
products, and saccharin as the terminal product.
These products are also observed as major
degradation products in soils. In plants,
monohydroxymethylsulfometuron methyl is the primary
metabolite which is also identified as a mammalian
and soil metabolite and undergoes further degradation
by mammals to give 2-amino-4-hydroxymethyl-6-
methylpyrimidine. |
| | DPX-T5648 Preparation Products And Raw materials |
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