ChemicalBook Product Catalog API Synthetic Anti-infective Drugs Sulfonamides and synergist Sulfaquinoxaline

Sulfaquinoxaline

Sulfaquinoxaline Basic information
Description Brand Name(s) in US Reference
Product Name:Sulfaquinoxaline
Synonyms:SULFABENZPYRAZINE;SULFACHINOXALIN;SULFACHINOXALINE;sulfa-q 20;SULFAQUINOXALIN;SULFAQUINOXALINE;N-(2-QUINOXALINYL)SULFANILAMIDE;N'-2-QUINOXALYL SULFANILAMINE
CAS:59-40-5
MF:C14H12N4O2S
MW:300.34
EINECS:200-423-2
Product Categories:Amines;Aromatics;Intermediates & Fine Chemicals;Pharmaceuticals;Sulfur & Selenium Compounds;PHENERGAN;59-40-5
Mol File:59-40-5.mol
Sulfaquinoxaline Structure
Sulfaquinoxaline Chemical Properties
Melting point 247-2480C
Boiling point 551.1±60.0 °C(Predicted)
density 1.3196 (rough estimate)
refractive index 1.6440 (estimate)
storage temp. Refrigerator
solubility DMSO (Slightly), Methanol (Slightly), Water (Slightly)
pka5.65±0.10(Predicted)
form neat
color Pale Yellow to Yellow
Merck 13,9025
BRN 290026
LogP1.680
CAS DataBase Reference59-40-5(CAS DataBase Reference)
EPA Substance Registry SystemSulfaquinoxaline (59-40-5)
Safety Information
Hazard Codes Xn
Risk Statements 22-42/43
Safety Statements 22-36/37-45
WGK Germany 3
RTECS WP2100000
HS Code 29350090
Hazardous Substances Data59-40-5(Hazardous Substances Data)
MSDS Information
ProviderLanguage
N1-(2-Quinoxalinyl)sulfanilamide English
Sulfaquinoxaline Usage And Synthesis
DescriptionSulfaquinoxaline is a kind of veterinary medicine which can be used for the treatment of coccidiosis in cattle and sheep. It is usually used in combination with Amprolium and Vitamin K. It is a protective agent against upper respiratory infections of poultry and a prophylactic against coccidiosis. It takes effects via inhibiting vitamin K epoxidase (epoxide reductase, menadione epoxide reductase) and quinone reductase. Sulfaquinoxaline played an important part in the demotion of roast chicken from vaunted Sunday-dinner status to an un-respected position on the everyday menu of the Western world. Although it has long been eclipsed by other drugs in poultry management, it continues to be used in other host species.
Brand Name(s) in USSulfa-Nox
ReferenceCampbell, W. C. "History of the discovery of sulfaquinoxaline as a coccidiostat." Journal of Parasitology 94.4(2008):934-945.
Chemical PropertiesCrystalline Solid
Usesantihistaminic
UsesCoccidiostat.
DefinitionChEBI: 4-amino-N-(2-quinoxalinyl)benzenesulfonamide is a sulfonamide and a member of benzenes.
Safety ProfileModerately toxic by ingestion. When heated to decomposition it emits very toxic fumes of NOx and SOx.
Sulfanilamide Sulfasalazine 3-Aminobenzenesulfonamide Methyl anthranilate Sulfanilic acid Sulfadiazine ALTRENOGEST 4-Aminobenzoic acid 6-Aminocaproic acid Glycine p-Anisidine Aniline SULFA Quinazoline Tris(hydroxymethyl)aminomethane AMINO ACIDS Anthranilic acid Fomesafen
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