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| | QUINETHAZONE (1.5 G) Basic information |
| Product Name: | QUINETHAZONE (1.5 G) | | Synonyms: | 7-Chloro-2-ethyl-6-sulfaMyl-1,2,3,4-tetrahydro-4-quinazolinone;QuinethazonuM;1,2,3,4-tetrahydro-7-chloro-2-ethyl-4-oxo-6-quinazolinesulfonamid;7-chloro-2-ethyl-1,2,3,4-tetrahydro-4-oxo-6-quinazolinesulfonamid;7-chloro-2-ethyl-1,2,3,4-tetrahydro-4-oxo-6-sulfamoylquinazoline;7-chloro-2-ethyl-6-sulfamoyl-1,2,3,4-tetrahydro-4-quinazolinone;aquamox;2-Ethyl-7-chloro-6-sulfamoyl-1,2-dihydroquinazoline-4(3H)-one | | CAS: | 73-49-4 | | MF: | C10H12ClN3O3S | | MW: | 289.73858 | | EINECS: | 2008017 | | Product Categories: | Aromatics;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Sulfur & Selenium Compounds | | Mol File: | 73-49-4.mol |  |
| | QUINETHAZONE (1.5 G) Chemical Properties |
| Melting point | 250-252° | | density | 1.4208 (rough estimate) | | refractive index | 1.6300 (estimate) | | storage temp. | Refrigerator | | solubility | DMSO (Slightly), Methanol (Slightly, Sonicated) | | form | Solid | | pka | pKa 9.3 (Uncertain);10.7 (Uncertain) | | color | Pale Beige to Brown | | Water Solubility | 0.15g/L(25 ºC) | | Stability: | Stable. Combustible. Incompatible with strong oxidizing agents. | | EPA Substance Registry System | Quinethazone (73-49-4) |
| | QUINETHAZONE (1.5 G) Usage And Synthesis |
| Chemical Properties | white powder | | Uses | Quinethazone is a thiazide diuretic used to treat hypertension. | | Definition | ChEBI: Quinethazone is a member of the class of quinazolines that is quinazolin-4-one substituted at positions 2, 6 and 7 by ethyl, sulfamoyl and chloro groups respectively; a thiazide-like diuretic used to treat hypertension. It has a role as an antihypertensive agent and a diuretic. | | Brand name | Hydromox (Lederle). | | General Description | Fibrous crystals or white powder. | | Air & Water Reactions | Insoluble in water. | | Fire Hazard | Flash point data for QUINETHAZONE (1.5 G) are not available; however, QUINETHAZONE (1.5 G) is probably combustible. |
| | QUINETHAZONE (1.5 G) Preparation Products And Raw materials |
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