L-Phenylglycine

L-Phenylglycine Basic information
Product Name:L-Phenylglycine
Synonyms:H-PHG-OH;H-(PHENYL)GLY-OH;H-L-PHG-OH;(+)-L-ALPHA-PHENYLGLYCINE;L-(+)-ALPHA-PHENYLGLYCINE;L(+)-ALPHA-AMINOPHENYLACETIC ACID;L-ALPHA-AMINOPHENYLACETIC ACID;L-AMINOPHENYLACETIC ACID
CAS:2935-35-5
MF:C8H9NO2
MW:151.16
EINECS:220-909-8
Product Categories:Amino Acids;Phenylglycine [Phg];GLYCINESCAFFOLD;Amino ACIDS SERIES;Aromatic Phenylacetic Acids and Derivatives;Unusual Amino Acids
Mol File:2935-35-5.mol
L-Phenylglycine Structure
L-Phenylglycine Chemical Properties
Melting point >300 °C(lit.)
alpha 157 º (c=2, 2N HCl)
Boiling point 273.17°C (rough estimate)
density 1.2023 (rough estimate)
refractive index 158 ° (C=1, 1mol/L HCl)
Fp 150 °C
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility Aqueous Acid, Aqueous Base
pka1.83(at 25℃)
form Fine Crystalline Powder
color White
optical activity[α]20/D +155°, c = 1 in 1 M HCl
Merck 14,7291
BRN 2208675
InChIKeyZGUNAGUHMKGQNY-ZETCQYMHSA-N
CAS DataBase Reference2935-35-5(CAS DataBase Reference)
EPA Substance Registry SystemL-Phenylglycine (2935-35-5)
Safety Information
Safety Statements 22-24/25
WGK Germany 3
TSCA Yes
HS Code 29224995
MSDS Information
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L-Phenylglycine Usage And Synthesis
DescriptionL-Phenylglycine is an amide that belongs to the group of pyridoxal phosphate analogues. It has been shown to be a response element for enzymes and natural compounds in Escherichia coli and Saccharomyces cerevisiae. It inhibits aminotransferase activity, dopamine synthesis, and microbial metabolism in these organisms. This compound also has a structural analysis that includes x-ray diffraction data, which can be used to identify its three-dimensional structure.
Chemical PropertiesWhite crystalline powder
UsesL-(+)-2-Phenylglycine is a derivative of Glycine (G615990), the smallest of all the amino acids, and is also used to treat schizophrenia, stroke, and benign prostatic hyperplasia. L-(+)-2-Phenylglycine is also used as an N-linked side chain of an SMTP (Stachybotrys microspora tripenyl phenols) congener, which was potent in enhancing plasminogen activation in S. microspora.
DefinitionChEBI: The S stereoisomer of alpha-phenylglycine.
Purification MethodsCrystallise it from EtOH. [Kaneko J Chem Soc Jpn 60 538 1939, Rudman et al. J Am Chem Soc 74 551 1952, Greenstein & Winitz The Chemistry of the Amino Acids J. Wiley, Vol 3 pp 2694-2697 1961, Beilstein 14 III 1187, 14 IV 1317.]
(S)-(+)-2-Phenylglycinol L-Phenylglycine Folic acid α-Lipoic Acid Glycine L-PHENYLGLYCINE METHYL ESTER HCL,L-PHENYLGLYCINE METHYL ESTER HYDROCHLORIDE,L-PHENYLGLYCINE METHYL ESTER HYDROCHLORIDE SALT Triphenyltin acetate o-Aminophenylacetic acid D-AMPHETAMINE HYDROCHLORIDE phosphoric acid Anilinoacetic acid Iminodiacetic acid 4-Hydroxy-D-(-)-2-phenylglycine Cyphenothrin Nitrilotriacetic acid D-2-Phenylglycine D-Phenothrin Citric acid

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