ChemicalBook Product Catalog Organic Chemistry Phosphines (4-Carboxybutyl)triphenylphosphonium bromide

(4-Carboxybutyl)triphenylphosphonium bromide

(4-Carboxybutyl)triphenylphosphonium bromide Basic information
Product Name:(4-Carboxybutyl)triphenylphosphonium bromide
Synonyms:(4-CARBOXYBUTYL)TRIPHENYLPHOSPHONIUM BROMIDE;(4-Carboxybutyl)triphenylphosp;PhosphoniuM,(4-carboxybutyl)triphenyl-, broMide (1:1);4-carboxybutyltripheyl phosphonium bromide;(4-(4-carboxybutyl)phenyl)diphenylphosphonium bromide;4-carboxybutyl(triphenyl)phosphanium,bromide;(4-Carboxybut;(4-Carboxybut-1-yl)(triphenyl)phosphonium bromide 98%
CAS:17814-85-6
MF:C23H24BrO2P
MW:443.31
EINECS:241-782-5
Product Categories:Miscellaneous Reagents;API intermediates;Miscellaneous Compounds;Phosphonium Compounds;Synthetic Organic Chemistry;Wittig & Horner-Emmons Reaction;Wittig Reaction;C-C Bond Formation;Olefination;Wittig Reagents
Mol File:17814-85-6.mol
(4-Carboxybutyl)triphenylphosphonium bromide Structure
(4-Carboxybutyl)triphenylphosphonium bromide Chemical Properties
Melting point 204-207 °C(lit.)
Boiling point 324.7-327.4℃ at 101.93-102.15kPa
density 1.371 at 20℃
vapor pressure 0Pa at 25℃
Fp 195°(383°F)
storage temp. Store below +30°C.
solubility DMSO, Methanol, Water
form solid
color White to Off-White
Water Solubility Soluble in ethanol, methanol and soluble water. Insoluble in toluene and hexane.
Sensitive Hygroscopic
BRN 3586477
InChIKeyKQJPHSBFOSLICV-UHFFFAOYSA-N
LogP0.146
CAS DataBase Reference17814-85-6(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36
RIDADR 3278
WGK Germany 3
HS Code 29310095
MSDS Information
ProviderLanguage
(4-Carboxybutyl)triphenylphosphonium bromide English
SigmaAldrich English
ALFA English
(4-Carboxybutyl)triphenylphosphonium bromide Usage And Synthesis
Chemical PropertiesWHITE TO ALMOST WHITE CRYSTALLINE POWDER
Usessuzuki reaction
Uses(4-Carboxybutyl)triphenylphosphonium Bromide (cas# 17814-85-6) is a compound useful in organic synthesis.
Uses
  • Used as a platform for delivery of pro-apoptotic peptides into the mitochondria of tumor cells

Reactant for preparation of:
  • Ring skeletons via ring closing metathesis and double bond migration ring closing metathesis reactions
  • Methyl alkenyl quinolones as antimycobacterial agents
  • Prostaglandins and their drug analogs via Gold-catalyzed Meyer-Schuster rearrangement
  • Diphenylmethylpiperazines as N-type calcium channel blockers as potential therapeutic agents
  • Folate receptor-specific glycinamide ribonucleotide formyltransferase (GARFTase) inhibitors with antitumor activity
  • Cycloalkylidene alkanols with antileishmanial activity, via Wittig reaction
(4-Carboxybutyl)triphenylphosphonium bromide Preparation Products And Raw materials
Preparation Products6-PHENYL-1-HEXANOL-->Travoprost Acid-->(+)-Cloprostenol-->5-cyclopentylpentanoic acid
brominated butyl rubber Methyltriphenylphosphonium bromide PHENYLMAGNESIUM BROMIDE Rocuronium bromide (4-Carboxybutyl)triphenylphosphonium bromide Tetrabutylammonium bromide Tetraphenylphosphonium bromide (4-ETHOXYCARBONYLBUTYL)TRIPHENYLPHOSPHONIUM BROMIDE BUTYLDIPHENYLPHOSPHINE DICHLOROTRIPHENYLPHOSPHORANE Benzyltributylammonium bromide Sodium bromate Ethidium bromide Ethyltriphenylphosphonium bromide Allyl bromide Triphenylphosphine hydrobromide Methyl bromide Butyltriphenylphosphonium bromide
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