ChemicalBook Product Catalog Pharmaceutical intermediates Heterocyclic compound Pyrimidines Esters Pyrimidine-5-boronic acid pinacol ester

Pyrimidine-5-boronic acid pinacol ester

Pyrimidine-5-boronic acid pinacol ester Basic information
Product Name:Pyrimidine-5-boronic acid pinacol ester
Synonyms:PYRIMIDINE-5-BORONIC ACID PINACOLATE;PYRIMIDIN-5-YLBORONIC ACID PINACOL ESTER;PYRIMIDYL-5-BORONIC ACID PINACOLATE;PYRIMIDYL-5-BORONIC ACID PINACOL ESTER;PYRIMIDINE-5-BORONIC ACID PINACOL ESTER;PINACOL ESTER PYRIMIDINYL-5-BORONIC ACID;5-Pyrimidineboronic acid pinacol ester;PyriMidine,5-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-
CAS:321724-19-0
MF:C10H15BN2O2
MW:206.05
EINECS:
Product Categories:blocks;BoronicAcids;Heterocycles;Boronic Acid
Mol File:321724-19-0.mol
Pyrimidine-5-boronic acid pinacol ester Structure
Pyrimidine-5-boronic acid pinacol ester Chemical Properties
Melting point 60-66°C
Boiling point 308.9±15.0 °C(Predicted)
density 1.07±0.1 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
form powder to crystal
pka1.63±0.10(Predicted)
color White to Orange to Green
CAS DataBase Reference321724-19-0(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
HazardClass IRRITANT
HS Code 2933599590
MSDS Information
Pyrimidine-5-boronic acid pinacol ester Usage And Synthesis
UsesPyrimidine-5-boronic acid pinacol ester is used in the preparation of indole derivatives as selective inhibitors of all three members of the Pim kinase family. It is also used to prepare inhibitors of TGF-β1 and activin A signalling.
Uses2-Methoxyphenylborornic Acid Pinacol Ester is used in the preparation of indole derivatives as selective inhibitors of all three members of the Pim kinase family. It is also used to prepare inhibitors of TGF-β1 and activin A signalling.
Pyrimidine-5-boronic acid pinacol ester Preparation Products And Raw materials
2-[4-(N-Boc)piperazin-1-yl]pyrimidine-5-boronic acid pinacol ester,2-(4-BOC-PIPERAZIN-1-YL)PYRIMIDINE-5-BORONIC ACID PINACOL ESTER 1-[5-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-PYRIMIDIN-2-YL]-PIPERIDINE-4-CARBOXYLIC ACID 2,4-Dimethoxy-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-pyrimidine Pyrimidine-5-boronic acid pinacol ester 4-BENZYLOXY-2-DIMETHYLAMINO-PYRIMIDINE-5-BORONIC ACID 2-DIMETHYLAMINO-PYRIMIDINE-5-BORONIC ACID PINACOL ESTER 2-(PIPERIDIN-1-YL)PYRIMIDINE-5-BORONIC ACID PINACOL ESTER 2-(4-METHYLPIPERAZIN-1-YL)PYRIMIDINE-5-BORONIC ACID PINACOL ESTER 2-(METHYLTHIO)PYRIMIDINE-5-BORONIC ACID PINACOL ESTER [2-(1H-INDOL-3-YL)-ETHYL]-[5-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-PYRIMIDIN-2-YL]-AMINE 2-(4-[5-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-PYRIMIDIN-2-YL]-PIPERAZIN-1-YL)-ETHANOL 2,4-DICHLORO-5-(4,4,5,5-TETRAMETHYL-[1,3,2]-DIOXABOROLAN-2-YL)PYRIMIDINE 2-TERT-BUTYLOXYCARBONYLAMINO-4-HYDROXY-6-METHYL PYRIMIDINE-5-BORONIC ACID PINACOL ESTER 2-Aminopyrimidine-5-boronic Acid Pinacol Ester 4-BENZYLOXY-2-CHLOROPYRIMIDINE-5-BORONIC ACID PINACOL ESTER 2-(4-MORPHOLINO)PYRIMIDINE-5-BORONIC ACID PINACOL ESTER 1-[5-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-PYRIMIDIN-2-YL]-1H-PYRROLE-2-CARBALDEHYDE 2-CYANOPYRIMIDINE-5-BORONIC ACID PINACOL ESTER
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