4-CHLORO-8-(TRIFLUOROMETHYL)QUINOLINE

4-CHLORO-8-(TRIFLUOROMETHYL)QUINOLINE Basic information
Product Name:4-CHLORO-8-(TRIFLUOROMETHYL)QUINOLINE
Synonyms:4-CHLORO-8-(TRIFLUOROMETHYL)QUINOLINE;BUTTPARK 14\09-64;4-CHLORO-8-(TRIFLUOROMETHYL)QUINOLINE, 9 7%;4-Chloro-8-(trifluoromethyl)quinoline 98%;4-Chloro-8-(trifluoromethyl)quinoline98%;4-Chloro-8-(trifluoroMethyl)quinolline;Quinoline, 4-chloro-8-(trifluoromethyl)-;4-CHLORO-8-(TRIFLUOROMETHYL)QUINOLINE ISO 9001:2015 REACH
CAS:23779-97-7
MF:C10H5ClF3N
MW:231.6
EINECS:245-880-9
Product Categories:Quinoline&Isoquinoline;Building Blocks;Halogenated Heterocycles;Heterocyclic Building Blocks;Quinolines;QuinolinesHeterocyclic Building Blocks
Mol File:23779-97-7.mol
4-CHLORO-8-(TRIFLUOROMETHYL)QUINOLINE Structure
4-CHLORO-8-(TRIFLUOROMETHYL)QUINOLINE Chemical Properties
Melting point 80-82 °C(lit.)
Boiling point 265.5±35.0 °C(Predicted)
density 1.427±0.06 g/cm3(Predicted)
storage temp. Inert atmosphere,Room Temperature
solubility Chloroform, Methanol
form Solid
pka1.30±0.30(Predicted)
color Brown
Water Solubility Low solubility in water.
CAS DataBase Reference23779-97-7(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36
WGK Germany 3
HazardClass IRRITANT
HS Code 29334900
MSDS Information
ProviderLanguage
SigmaAldrich English
ALFA English
4-CHLORO-8-(TRIFLUOROMETHYL)QUINOLINE Usage And Synthesis
Chemical Propertieswhite to light yellow crystal powder
Uses4-Chloro-8-(trifluoromethyl)quinoline is used as a reagent for the potent CRTh2 (DP2) receptor antagonists discovery which is used for treatment of asthma, allergic rhinitis and other inflammatory diseases.
4-CHLORO-8-(TRIFLUOROMETHYL)QUINOLINE Preparation Products And Raw materials
Raw materialsMethanol-->Phosphorus oxychloride-->Sodium bisulfite-->Iodine-->Cyclohexane-->Hydroquinone-->Acrylic acid-->2-Aminobenzotrifluoride
Preparation Products4-HYDRAZINO 8-TRIFLUOROMETHYL-QUINOLINE
8-chloro-4-(trifluoromethyl)quinoline-3-carboxylic acid 4-(2-AMINOETHYLTHIO)-8-CHLORO-2-(TRIFLUOROMETHYL)QUINOLINE 2,8-BIS(TRIFLUOROMETHYL)-4-CHLOROQUINOLINE ETHYL 4-CHLORO-2-(TRIFLUOROMETHYL)QUINOLINE-6-CARBOXYLATE ETHYL 4-CHLORO-2-(METHYLSULFINYL)-8-(TRIFLUOROMETHYL)QUINOLINE-3-CARBOXYLATE 4-CHLORO-3-(2-CHLOROETHYL)-2-METHYL-8-(TRIFLUOROMETHYL)QUINOLINE 4-CHLORO-8-(TRIFLUOROMETHYL)QUINOLINE 8-CHLORO-2-(TRIFLUOROMETHYL)QUINOLINE-4-CARBONITRILE 4-CHLORO-2-TRICHLOROMETHYL-8-TRIFLUOROMETHYL-QUINOLINE 4-CHLORO-7-(TRIFLUOROMETHYL)QUINOLINE, 9 8%,4-Chloro-7-(trifluoromethyl)quinoline 98%,4-CHLORO-7-(TRIFLUOROMETHYL)QUINOLINE 4-(2-AMINOETHYLTHIO)-6-CHLORO-2-(TRIFLUOROMETHYL)QUINOLINE 4-CHLORO-2-PROPYL-8-TRIFLUOROMETHYLQUINOLINE 4-CHLORO-2-METHYL-8-(TRIFLUOROMETHYL)QUINOLINE 6-Chloro-8-(trifluoromethyl)quinoline ETHYL 4-CHLORO-2-(METHYLTHIO)-8-(TRIFLUOROMETHYL)QUINOLINE-3-CARBOXYLATE 4-BROMO-6-CHLORO-2-(TRIFLUOROMETHYL)QUINOLINE 4-CHLORO-8-(TRIFLUOROMETHYL)QUINOLINE-3-CARBOXYLIC ETHYL ESTER 6-BROMO-4-CHLORO-2-(TRIFLUOROMETHYL)QUINOLINE

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