BOC-TRANS-4-FLUORO-L-PROLINE

BOC-TRANS-4-FLUORO-L-PROLINE Basic information

Product Name:	BOC-TRANS-4-FLUORO-L-PROLINE
Synonyms:	N-BOC-(4S,2R)-4-FLUORO-2-PYRROLIDINECARBOXYLIC ACID;N-BOC-TRANS-4-FLUORO-L-PROLINE;N-T-BOC-TRANS-4-FLUORO-L-PROLINE;N-(TERT-BUTOXYCARBONYL)-(2S,4R)-4-FLUOROPROLINE;BOC-TRANS-4-FLUORO-L-PROLINE;(2S,4R)-N-Boc-trans-4-Fluoro-L-Proline;(2S,4R)-4-Fluoropyrrolidine-2-carboxylic acid, N4-BOC protected;trans-4-Fluoro-L-proline, N-BOC protected
CAS:	203866-14-2
MF:	C10H16FNO4
MW:	233.24
EINECS:
Product Categories:	Carboxylic Acids (Chiral);Chiral Building Blocks;Synthetic Organic Chemistry;Chiral Building Blocks;Heterocyclic Building Blocks;Pyrrolidines
Mol File:	203866-14-2.mol

BOC-TRANS-4-FLUORO-L-PROLINE Chemical Properties

Melting point	115-119°C
Boiling point	346.0±42.0 °C(Predicted)
density	1.24±0.1 g/cm3(Predicted)
refractive index	-69 ° (C=1, MeOH)
storage temp.	Inert atmosphere,Room Temperature
solubility	soluble in Methanol
form	powder to crystal
pka	3.53±0.40(Predicted)
color	White to Almost white
optical activity	[α]22/D -65.0±5°, c = 1 in chloroform
InChIKey	YGWZXQOYEBWUTH-RQJHMYQMSA-N
CAS DataBase Reference	203866-14-2(CAS DataBase Reference)

Safety Information

MSDS Information

BOC-TRANS-4-FLUORO-L-PROLINE Usage And Synthesis

Chemical Properties	White powder
Uses	N-Boc-trans-4-fluoro-L-proline is a useful synthetic intermediate. It is used to prepare potent 3- or 4-substituted-2-cyanopyrrolidine dipeptidyl peptidase IV inhibitors. It is also used to synthesize pyrrolotriazines derivatives as pan-Aurora kinase inhibitors and anti-tumor agents.

BOC-TRANS-4-FLUORO-L-PROLINE Preparation Products And Raw materials

Raw materials

Login