2,2'-Cyclouridine

2,2'-Cyclouridine Basic information
Product Name:2,2'-Cyclouridine
Synonyms:O2,2'-CYCLOURIDINE;2,2'-ANHYDRO-1(BETA-D-ARABINOFURANOSYL)URACIL;2,2'-ANHYDROURIDINE;2, 2'-ANHYDRO-1-(B-D-ARABINOFURANOSYL) URACIL;2,2'-Cyclouridine;BETA-D-O(2),2'-CYCLOURIDINE;02,2-Cycloridine;[2R-(2alpha,3beta,3abeta,9abeta)]-2,3,3a,9a-tetrahydro-3-hydroxy-(hydroxymethyl)-6H-furo[2',3':4,5]oxazolo[3,2-a]pyrimidin-6-one
CAS:3736-77-4
MF:C9H10N2O5
MW:226.19
EINECS:223-107-6
Product Categories:Building Blocks;C9 to C11;Heterocyclic Building Blocks;Pyrimidines;Chemical Synthesis;Heterocyclic Building Blocks;Heterocyclic Compounds;Biochemistry;Nucleosides and their analogs;Nucleosides, Nucleotides & Related Reagents;Building Blocks;3736-77-4
Mol File:3736-77-4.mol
2,2'-Cyclouridine Structure
2,2'-Cyclouridine Chemical Properties
Melting point 248-251 °C(lit.)
alpha -21°(19℃, c=4, H2O)
Boiling point 456.3±55.0 °C(Predicted)
density 2.01±0.1 g/cm3(Predicted)
refractive index -20 ° (C=4, H2O)
storage temp. -20°C
solubility DMSO:2.0(Max Conc. mg/mL);8.84(Max Conc. mM)
PBS (pH:7.2):1.0(Max Conc. mg/mL);4.42(Max Conc. mM)
pka12.55±0.40(Predicted)
form powder to crystal
color White to Almost white
optical activity[α]19/D 21°, c = 4 in H2O
InChIInChI=1S/C9H10N2O5/c12-3-4-6(14)7-8(15-4)11-2-1-5(13)10-9(11)16-7/h1-2,4,6-8,12,14H,3H2/t4-,6-,7+,8-/m1/s1
InChIKeyUUGITDASWNOAGG-CCXZUQQUSA-N
SMILESC12O[C@@]3([H])[C@H](O)[C@@H](CO)O[C@@]3([H])N1C=CC(=O)N=2
CAS DataBase Reference3736-77-4
Safety Information
Safety Statements 24/25
WGK Germany 3
HS Code 29349990
MSDS Information
ProviderLanguage
SigmaAldrich English
2,2'-Cyclouridine Usage And Synthesis
Description2,2'-Anhydro-1(B-D-arabinofuranosyl)uracil is a research tool for anticancer and antiviral studies. This works by inhibiting uridine phosphorylase, a key enzyme targeted by some antitumor drugs.
Chemical PropertiesWhite powder
UsesO2,2''-Cyclouridine is a research tool for anticancer and antiviral studies.
UsesResearch tool for antiviral and anticancer studies.1
2,2'-Cyclouridine Preparation Products And Raw materials
Raw materials1-beta-D-Arabinofuranosyluracil
1,3-Dimethoxypropane 4-Methoxy-2-pentanol 3-Dimethylamino-1-propanol (S)-(+)-1-Methoxy-2-propanol N-(2-METHOXYETHYL)METHYLAMINE URACIL 3-Dimethylaminopropane-1,2-diol 2,2'-Cyclouridine (R)-(-)-1-METHOXY-2-PROPANOL 1,2-Dimethoxypropane Doxifluridine 4-METHYLAMINO BUTANOL 2-ISOPROPOXYETHANOL 6-METHOXYCARBONYL-O-2,2'-ANHYDRO-BETA-D-ARABINOFURANOSYL URACIL (R)-(-)-2-Methoxypropanol 3-ETHOXY-1,2-PROPANEDIOL 1,3-Dimethoxybutane 1,2-DIDEOXY-D-RIBOSE

Email:[email protected] [email protected]
Copyright © 2024 Mywellwork.com All rights reserved.