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| | Dithioerythritol Basic information |
| Product Name: | Dithioerythritol | | Synonyms: | (S,R)-DITHIOERYTHRITOL;(r*,s*)-1,4-dimercapto-2,3-butanediol;1,4-dimercapto-,(r*,s*)-3-butanediol;1,4-dimercapto-,(theta,s)-3-butanediol;1,4-dithio-erythrito;DITHIOERYTHRITOL MOLECULAR BIOLOGY*REAGE NT;DITHIOERYTHRITOL, 99+%;DITHIOERYTHRITOL SIGMAULTRA | | CAS: | 6892-68-8 | | MF: | C4H10O2S2 | | MW: | 154.25 | | EINECS: | 229-998-8 | | Product Categories: | Pharmaceutical Intermediates;Antioxidant;Biochemistry;Erythrose;O-Substituted Sugars;Sugar Alcohols;Sugars;proteinmod | | Mol File: | 6892-68-8.mol |  |
| | Dithioerythritol Chemical Properties |
| Melting point | 82-84 °C(lit.) | | Boiling point | 247.65°C (rough estimate) | | density | 1.156 (estimate) | | refractive index | 1.5200 (estimate) | | storage temp. | 2-8°C | | solubility | H2O: 10 mg/mL, clear, colorless | | pka | pK1:9.5 (25°C) | | form | Powder | | color | White to pale yellow or beige | | PH | 4.0-6.0 (25℃, 0.1M in H2O) | | Water Solubility | Soluble | | Sensitive | Air Sensitive | | λmax | λ: 260 nm Amax: 0.400
λ: 280 nm Amax: 0.050 | | BRN | 1719756 | | Stability: | Stable. Combustible. Incompatible with strong oxidizing agents. | | InChIKey | VHJLVAABSRFDPM-ZXZARUISSA-N | | CAS DataBase Reference | 6892-68-8(CAS DataBase Reference) | | EPA Substance Registry System | 1,4-Dithioerythritol (6892-68-8) |
| | Dithioerythritol Usage And Synthesis |
| Chemical Properties | White solid | | Uses | Reagent for maintaining ?SH groups in the reduced state; quantitatively reduces disulfides. | | Uses | Reagent for the reduction of disulfide group. Prevents oxidation of sulfhydryl-containing proteins during SDS-polyacrylamide gel electrophoresis. Cleavage of disulfide bonds in proteins | | Uses | 1,4-Dithioerythritol is a Michael reaction acceptor; inducers of enzymes that protect against carcinogenesis: reactivity with sulfhydryl groups. | | Definition | ChEBI: The meso-diastereomer of 1,4-dimercaptobutane-2,3-diol; a sulfur-containing sugar derived from the monosaccharide erythrose; and an epimer of dithiothreitol. | | Purification Methods | Crystallise DTE from ether/hexane and store it in the dark at 0o. [Beilstein 1 III 2360.] |
| | Dithioerythritol Preparation Products And Raw materials |
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