2,5-Difluoro-4-nitrobenzoic acid

2,5-Difluoro-4-nitrobenzoic acid Basic information
Product Name:2,5-Difluoro-4-nitrobenzoic acid
Synonyms:2,5-DIFLUORO-4-NITROBENZENECARBOXYLIC ACID;2,5-DIFLUORO-4-NITROBENZOIC ACID;2,5-Difluoro-4-Nitrobenzenecar;2,5-Difluoro-4-nitrobenzoic acid 98%;2,5-Difluoro-4-nitrobenzenecarboxylic;4-Carboxy-2,5-difluoronitrobenzene;Benzoic acid, 2,5-difluoro-4-nitro-;2,5-Difluoro-4-nitrobenzenecarboxylicaci
CAS:116465-48-6
MF:C7H3F2NO4
MW:203.1
EINECS:
Product Categories:Fluorine series;API intermediates
Mol File:116465-48-6.mol
2,5-Difluoro-4-nitrobenzoic acid Structure
2,5-Difluoro-4-nitrobenzoic acid Chemical Properties
Melting point 147-148
Boiling point 364.8±42.0 °C(Predicted)
density 1.661±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
pka2.03±0.13(Predicted)
form Solid
color White to pale green
Water Solubility Slightly soluble in water.
CAS DataBase Reference116465-48-6
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-37-60
TSCA No
HazardClass IRRITANT
HS Code 2916399090
MSDS Information
2,5-Difluoro-4-nitrobenzoic acid Usage And Synthesis
Uses2,5-Difluoro-4-nitrobenzoic acid is used as a pharmaceutical intermediate.
Synthesis Reference(s)Journal of Medicinal Chemistry, 35, p. 2321, 1992 DOI: 10.1021/jm00090a024
2,5-Difluoro-4-nitrobenzoic acid Preparation Products And Raw materials
Raw materials2,5-Difluorotoluene-->2,5-difluoro-4-nitrobenzonitrile-->1,4-DIFLUORO-2-METHYL-5-NITROBENZENE-->1-Bromo-2,5-difluorobenzene-->1,4-Difluorobenzene
2,5-difluoro-3-nitrobenzoic acid 2,6-Difluoro-3-nitrobenzoic acid 98%,2,6-DIFLUORO-3-NITROBENZOIC ACID 4,5-DIFLUORO-2-NITROBENZOIC ACID METHYL ESTER 2-Fluoro-4-nitrobenzoic acid 4-AMINO-2-FLUOROBENZOIC ACID 2,5-Difluoro-4-nitrobenzoic acid 2,4-DIFLUORO-5-NITROBENZOIC ACID METHYL ESTER 4,5-DIFLUORO-2-NITROBENZOIC ACID ETHYL ESTER 3,5-DIFLUORO-2-NITROBENZOIC ACID 3-FLUORO-4-NITRO-BENZALDEHYDE 1,4-DIFLUORO-2-METHYL-5-NITROBENZENE METHYL 2,5-DIFLUORO-4-NITROBENZENECARBOXYLATE 4-Amino-2,5-Difluorobenzoic Acid 2,6-DIFLUORO-3-NITROBENZOIC ACID ETHYL ESTER 3,4-Difluoronitrobenzene 4-Nitrophenyl chloroformate 3,5-Dinitrobenzoic acid 3-Fluoro-4-nitrobenzoic acid

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