ChemicalBook Product Catalog Pharmaceutical intermediates Heterocyclic compound Piperazine compounds 1-Phenylpiperazine

1-Phenylpiperazine

1-Phenylpiperazine Basic information
Product Name:1-Phenylpiperazine
Synonyms:TIMTEC-BB SBB003943;N-PHENYLPIPERAZINE;LABOTEST-BB LTBB000705;1-Fenylpiperazin;AKOS BBS-00003581;1-PHENYLPIPERAZINE;Levodropropizine EP Impurity B;Levodropropizine ImpurityⅡ:l-phenylpiperazine
CAS:92-54-6
MF:C10H14N2
MW:162.23
EINECS:202-165-6
Product Categories:Bioactive Small Molecules;Building Blocks;C10;Cell Biology;Chemical Synthesis;Heterocyclic Building Blocks;Piperaizine;API intermediates;(intermediate of levodropropizine);Piperazines;P;92-54-6
Mol File:92-54-6.mol
1-Phenylpiperazine Structure
1-Phenylpiperazine Chemical Properties
Melting point 18.8 °C
Boiling point 286 °C(lit.)
density 1.062 g/mL at 25 °C(lit.)
refractive index n20/D 1.588(lit.)
Fp >230 °F
storage temp. 2-8°C
solubility Insoluble
form Liquid
pkapK1:8.71(+1) (25°C,μ=0.1)
color Clear colorless to yellow
Specific Gravity1.062 (20/4℃)
Water Solubility Insoluble
BRN 132157
CAS DataBase Reference92-54-6(CAS DataBase Reference)
NIST Chemistry ReferencePiperazine, 1-phenyl-(92-54-6)
EPA Substance Registry SystemPiperazine, 1-phenyl- (92-54-6)
Safety Information
Hazard Codes T,C
Risk Statements 22-24-34-36/37/38-23/24/25
Safety Statements 26-36/37/39-45-28A
RIDADR UN 2922 8/PG 2
WGK Germany 3
RTECS TM2625000
Hazard Note Toxic/Corrosive
TSCA Yes
HazardClass 6.1
PackingGroup II
HS Code 29335995
MSDS Information
ProviderLanguage
1-Phenylpiperazine English
SigmaAldrich English
ACROS English
ALFA English
1-Phenylpiperazine Usage And Synthesis
Chemical Propertiesclear colorless to yellow liquid
Safety ProfilePoison by ingestion and skin contact. A skin and severe eye irritant. Mutation data reported. Combustible when exposed to heat or flame. It supports combustion and decomposes to yield toxic fumes of NOx. To fight fire, use water, foam, dry chemical. See also PIPERAZINE
1-Phenylpiperazine Preparation Products And Raw materials
Preparation ProductsDropropizine-->4-(4-BROMO-PHENYL)-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER-->1-(4-BROMOPHENYL)PIPERAZINE-->naphthalen-1-yl(4-phenylpiperazin-1-yl)methanone-->2-METHYL-2-(4-PHENYLPIPERAZINO)PROPANENITRILE-->1-(2-phenoxyethyl)-4-phenyl-piperazine-->N-(4-METHYLPHENYL)-2-(4-PHENYLPIPERAZINO)ACETAMIDE-->N-(3,5-dichlorophenyl)-2-(4-phenylpiperazin-1-yl)acetamide-->N-(4-METHOXYPHENYL)-2-(4-PHENYLPIPERAZINO)ACETAMIDE-->TERT-BUTYL 4-PHENYLPIPERAZINE-1-CARBOXYLATE
Levodropropizine Piperacillin N-Aminoethylpiperazine 1-Phenylpiperazine PIPERAZINE HEXAHYDRATE 1-(4-Aminophenyl)-4-(4-hydroxyphenyl)piperazine Phenylacetone 1-[2-(4-chloro-2-methylphenoxy)propanoyl]-4-phenylpiperazine 1-(4-Methoxyphenyl)-4-(4-nitrophenyl)piperazine 1-Methylpiperazine 1-PHENYL-2-PROPANOL 1-Boc-4-(2-formylphenyl)piperazine Dapiprazole 1-((1-CYCLOHEXYL-1H-TETRAZOL-5-YL)(PYRIDIN-3-YL)METHYL)-4-PHENYLPIPERAZINE 1-Phenyl-2-nitropropene Levodropropizine (R)-1-BENZYL-2-METHYL-4-(4-NITROPHENYL)PIPERAZINE Posaconazole
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