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L-Ornithine

L-Ornithine Basic information
Chemical Properties Uses
Product Name:L-Ornithine
Synonyms:(S)-2,5-Diaminovaleric acid;ORNITHINE;L-ORNITHINE;2,5-diaminopentanoic acid;(2S)-2,5-Diaminopentanoic acid;5-Amino-L-norvaline;Ornithine Phenylacetate;Arginine EP Impurity C
CAS:70-26-8
MF:C5H12N2O2
MW:132.16
EINECS:200-731-7
Product Categories:Inhibitors;Amino Acids;Nutritional Supplements
Mol File:70-26-8.mol
L-Ornithine Structure
L-Ornithine Chemical Properties
Melting point 140°C
Boiling point 244.08°C (rough estimate)
alpha D25 +11.5° (c = 6.5)
density 1.1740 (rough estimate)
refractive index 1.4496 (estimate)
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
solubility Water: 50 mg/mL (378.33 mM); DMSO: < 1 mg/mL (insoluble or slightly soluble)
pka1.705(at 25℃)
LogP-4.220
CAS DataBase Reference70-26-8(CAS DataBase Reference)
EPA Substance Registry SystemL-Ornithine (70-26-8)
Safety Information
Toxicitysce-hmn-lym 10 mg/L MUREAV 372,75,1996
MSDS Information
L-Ornithine Usage And Synthesis
Chemical PropertiesCrystals from alcoholether. Soluble in water and alcohol.
UsesBiochemical research; medicine.
Useshepatoprotectant, anticholesteremic
DefinitionChEBI: An optically active form of ornithine having L-configuration.
Synthesis Reference(s)Canadian Journal of Chemistry, 31, p. 1060, 1953 DOI: 10.1139/v53-139
Safety ProfileMutation data reported. When heated to decomposition it emits toxic vapors of NOx.
Purification MethodsCrystallise L-ornithine from water containing 1mM EDTA (to remove metal ions). [Perrin J Chem Soc 3125 1958, Rivard Biochemical Preparations 3 97 1955, Greenstein & Winitz The Chemistry of the Amino Acids J. Wiley, Vol 3 pp 2477-2491 1961, Beilstein 4 III 1346, 4 IV 2644.]
L-Ornithine Preparation Products And Raw materials
Preparation ProductsEflornithine-->Fmoc-Orn(Fmoc)-OH-->Nalpha-Fmoc-Ndelta-Boc-L-ornithine
4,4'-Diaminodiphenylsulfone Ethyl 2-(Chlorosulfonyl)acetate TOS-ARG-OME HCL Ascoric Acid N-ALPHA-BENZOYL-L-ARGININE N-ALPHA-ACETYL-L-ARGININE Folic acid TOS-ARG-OH Lithium diisopropylamide 4,4'-Methylenedianiline L-Arginine L-glutamate phosphoric acid Iminodiacetic acid H-GAMMA-GLU-PHE-OH Iminodiacetonitrile L(+)-Arginine N,N-Dimethyl-1,4-phenylenediamine 5-AMINOVALERIC ACID
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