Sodium methylparaben

Sodium methylparaben Basic information
Product Name:Sodium methylparaben
Synonyms:4-hydroxybenzoic acid methyl ester sodium salt;methyl p-hydroxybenzoate sodium salt;METHYLPARABEN, SODIUM SALT;(p-carboxyphenoxy)-sodiumethylester;benzoicacid,4-hydroxy-,methylester,sodiumsalt;Benzoicacid,p-hydroxy-,methylester,sodiumderiv.;bonomoldomna;METHYL 4-HYDROXYBENZOATE SODIUM SALT, PH EUR
CAS:5026-62-0
MF:C8H9NaO3
MW:176.15
EINECS:225-714-1
Product Categories:API;Cosmetics;Benzoic acid Series;Aromatic Esters;bc0001
Mol File:5026-62-0.mol
Sodium methylparaben Structure
Sodium methylparaben Chemical Properties
Melting point >125°C
density 1.42 g/cm3 (20 °C)
storage temp. Store at +15°C to +25°C.
solubility Freely soluble in water, sparingly soluble in ethanol (96 per cent), practically insoluble in methylene chloride.
pka8.4[at 20 ℃]
form Powder
color White
PH9.7-10.3 (1g/l, H2O)
Water Solubility 418g/L at 20℃
BRN 4165000
InChIKeyPESXGULMKCKJCC-UHFFFAOYSA-M
LogP-0.63 at 20℃
CAS DataBase Reference5026-62-0(CAS DataBase Reference)
EPA Substance Registry SystemMethylparaben sodium (5026-62-0)
Safety Information
Hazard Codes Xn
Risk Statements 22
Safety Statements 22-24/25
WGK Germany 1
RTECS DH2455000
Autoignition Temperature>600 °C
HS Code 29182930
ToxicityLD50 orally in Rabbit: > 5000 mg/kg
MSDS Information
ProviderLanguage
4-Hydroxybenzoic acid methyl ester sodium salt English
SigmaAldrich English
ACROS English
Sodium methylparaben Usage And Synthesis
Chemical Propertieswhite powder
UsesMethyl 4-hydroxybenzoate has antimicrobial characteristics and is used as preservative in pharmaceutical formulations and cosmetics. It can be combined with other parabens like propyl 4-hydroxybenzoate or ethyl 4-hydroxybenzoate. The sodium salt provides improved solubility in water compared to standard methyl 4-hydroxybenzoate.
UsesPharmaceutic aid.
Flammability and ExplosibilityNonflammable
Contact allergensThis substance is one of the parabens family. Parabens are esters formed by p-hydroxybenzoic acid and an alcohol. They are largely used as biocides in cosmetics and toiletries, medicaments, or food. They have synergistic power with other biocides. Parabens can induce allergic contact dermatitis, mainly in chronic dermatitis and wounded skin.
Sodium methylparaben Preparation Products And Raw materials
Preparation ProductsMethyl 3,4-dihydroxybenzoate
Methyl 2'-Hydroxy-3-phenylpropiophenone 4-Morpholineethanesulfonic acid sodium 3-Hydroxybenzoic acid Ethyl 4-hydroxybenzoate,sodium salt 8-CHLOROADENOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE, RP-ISOMER SODIUM SALT METHYL THIOPHENE-2-CARBOXYLATE Acetylsalicylic Acid Impurity 7 Sasapyrine Acetylsalicylic Acid Impurity 9 4-amino-6-hydroxybenzene-1,3-dicarboxylic acid 4-HYDROXYBENZOIC-2,3,5,6-D4 ACID Aspirin-acyl--D-glucuronide 4-Hydroxyisophthalic acid 2-[[2-(Acetyloxy)benzoyl]oxy]benzoic acid 2-Carboxyphenyl Ester 2-ACETOXYBENZOIC-3,4,5,6-D4 ACID Acetylsalicylic Acid Impurity 1 Sodium Methyl Paraben

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