ChemicalBook Product Catalog Biochemical Engineering Inhibitors protein tyrosine kinase 2-(2-ETHYL-2,3-DIHYDRO-2-BENZOFURANYL)-1H-IMIDAZOLE

2-(2-ETHYL-2,3-DIHYDRO-2-BENZOFURANYL)-1H-IMIDAZOLE

2-(2-ETHYL-2,3-DIHYDRO-2-BENZOFURANYL)-1H-IMIDAZOLE Basic information
Product Name:2-(2-ETHYL-2,3-DIHYDRO-2-BENZOFURANYL)-1H-IMIDAZOLE
Synonyms:2-(2-ETHYL-2,3-DIHYDRO-2-BENZOFURANYL)-1H-IMIDAZOLE;KU14R;1H-IMidazole,2-(2-ethyl-2,3-dihydro-2-benzofuranyl)-;CS-891;KU-14R; KU 14R;2-(2-ethyl-3H-1-benzofuran-2-yl)-1H-imidazole;2-(2-ETHYL-2,3-DIHYDRO-2-BENZOFURANYL)-1H-IMIDAZOLE USP/EP/BP
CAS:189224-48-4
MF:C13H14N2O
MW:214.26
EINECS:
Product Categories:Imidazoline binding site
Mol File:189224-48-4.mol
2-(2-ETHYL-2,3-DIHYDRO-2-BENZOFURANYL)-1H-IMIDAZOLE Structure
2-(2-ETHYL-2,3-DIHYDRO-2-BENZOFURANYL)-1H-IMIDAZOLE Chemical Properties
Boiling point 428.1±34.0 °C(Predicted)
density 1.181±0.06 g/cm3(Predicted)
storage temp. Store at RT
solubility Soluble to 100 mM in DMSO
form Powder
pka13.14±0.10(Predicted)
Safety Information
MSDS Information
2-(2-ETHYL-2,3-DIHYDRO-2-BENZOFURANYL)-1H-IMIDAZOLE Usage And Synthesis
UsesKU14R is a putative imidazoline I3 receptor antagonist, which blocks the effects of the atypical I3 agonist efaroxan.
DefinitionChEBI: 2-(2-ethyl-3H-benzofuran-2-yl)-1H-imidazole is a member of 1-benzofurans.
Biological ActivityAntagonist of the atypical imidazoline binding site (putative I 3 receptor) of pancreatic β -cells. Selectively blocks efaroxan-induced insulin secretion in vitro and in vivo .
2-(2-ETHYL-2,3-DIHYDRO-2-BENZOFURANYL)-1H-IMIDAZOLE Preparation Products And Raw materials
Phthalan 2,3-Dihydrofuran Tetrahydrofuran 2-(2-ETHYL-2,3-DIHYDRO-2-BENZOFURANYL)-1H-IMIDAZOLE 2-(2,3-DIHYDRO-BENZOFURAN-2-YL)-1H-IMIDAZOLE
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