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| | Eprazinone Basic information |
| Product Name: | Eprazinone | | Synonyms: | EPRAZINONE;1-(2-phenyl-2-ethoxy)ethyl-4-(2-benzoyl)propylpiperazine;β-[4-(β-Ethoxyphenethyl)-1-piperazinyl]-α-methylpropiophenone;3-(4-(2-Ethoxy-2-phenylethyl)piperazin-1-yl)-2-Methyl-1-phenylpropan-1-one;1-Propanone, 3-[4-(2-ethoxy-2-phenylethyl)-1-piperazinyl]-2-methyl-1-phenyl-;1-(2-phenyl-2-ethoxyethyl)-4-(2-benzyloxypropyl)piperazine;2-(4-(beta-ethoxyphenethyl)-1-piperazinyl)methyl-propiophenon;3-(4-(2-ethoxy-2-phenylethyl)-1-piperazinyl)-2-methyl-1-phenyl-1-propano ne | | CAS: | 10402-90-1 | | MF: | C24H32N2O2 | | MW: | 380.52 | | EINECS: | 233-873-3 | | Product Categories: | | | Mol File: | 10402-90-1.mol |  |
| | Eprazinone Chemical Properties |
| Boiling point | 508.13°C (rough estimate) | | density | 1.0909 (rough estimate) | | refractive index | 1.5500 (estimate) | | storage temp. | Sealed in dry,Room Temperature | | pka | 6.83±0.10(Predicted) | | CAS DataBase Reference | 10402-90-1(CAS DataBase Reference) |
| | Eprazinone Usage And Synthesis |
| Originator | Mucitux,Riom,France,1969 | | Definition | ChEBI: A member of the class of piperazines in which the two amino hydrogens of piperazine are replaced by 2-benzoylpropyl and 2-ethoxy-2-phenylethyl groups. | | Manufacturing Process | 61.4 g of 0.2M of 1-(2-phenyl-2-ethoxy)piperazine dihydrochloride, 33.5 g
(0.25M) propiophenone, 75 g (0.25M) trioxymethylene, 120 ml of ethanol and
0.4 ml of concentrated HCl are heated under reflux for 4 to 5 hours. The
product is allowed to crystallize, then filtered and washed with alcohol. It is
dried and recrystallized from methanol containing 10% H2O.
There is thus obtained 60 g of a white crystalline powder soluble in water.
Yield: 66%. Melting point: 160°C. | | Therapeutic Function | Antitussive |
| | Eprazinone Preparation Products And Raw materials |
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