ChemicalBook Product Catalog Pharmaceutical intermediates Heterocyclic compound Pyran compounds 6-HYDROXYFLAVANONE

6-HYDROXYFLAVANONE

6-HYDROXYFLAVANONE Basic information
Product Name:6-HYDROXYFLAVANONE
Synonyms:HYDROXYFLAVANONE, 6-;6'-HYDROXYFLAVANONE;6-HYDROXYFLAVANONE;2-Phenyl-6-hydroxy-3,4-dihydro-2H-1-benzopyran-4-one;6-OH Flavanone;6-hydroxy-2-phenylchroMan-4-one;6-Hydroxyflavanone 99%;6-Hydroxyflavanone,98+%
CAS:4250-77-5
MF:C15H12O3
MW:240.25
EINECS:624-472-8
Product Categories:Flavanones;Biochemistry;Flavonoids;Benzopyrans;Building Blocks;Heterocyclic Building Blocks
Mol File:4250-77-5.mol
6-HYDROXYFLAVANONE Structure
6-HYDROXYFLAVANONE Chemical Properties
Melting point 220-222 °C (dec.) (lit.)
Boiling point 464.3±45.0 °C(Predicted)
density 1.288±0.06 g/cm3(Predicted)
pka9.53±0.40(Predicted)
form powder to crystal
color White to Orange to Green
BRN 87354
LogP2.955 (est)
CAS DataBase Reference4250-77-5(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36
WGK Germany 3
HS Code 29329900
MSDS Information
ProviderLanguage
ACROS English
SigmaAldrich English
ALFA English
6-HYDROXYFLAVANONE Usage And Synthesis
Chemical PropertiesSlightly yellow-cream powder
Uses6-Hydroxyflavanone (6-HF) has been used for the enantiomeric separation of flavonoids using polysaccharide-based chiral stationary phases by nano-liquid chromatography (nano-LC). Racemic 6-HF may be used in the synthesis of 6-propionoxy-flavanone (6-PF). 6-HF may be employed as synthetic flavone to investigate the mechanism of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) induced cytotoxic and apoptotic effects in HeLa cancer cells.
DefinitionChEBI: A monohydroxyflavanone that is flavanone substituted by a hydroxy group at position 6.
General Description6-Hydroxyflavanone is a flavonoid. Its biotransformation by Aspergillus niger strains have been described. Crystal structure of S and R enanti-omers of 6-hydroxyflavanone has been reported to have four crystallographic sites of the unit cell in an approximate 3:1/1:3 ratio. It was identified as a metabolite of flavnone on incubation with rat liver microsomes by positive ion electrospray LC/MS analysis.
6-HYDROXYFLAVANONE Preparation Products And Raw materials
Preparation Products3,6-DIHYDROXYFLAVONE
6,3'-DIMETHOXYFLAVANONE 6-HYDROXYFLAVANONE HYDROXYFLAVANONE, 2'-(RG),HYDROXYFLAVANONE, 2'-,2'-HYDROXYFLAVANONE,2-HYDROXYFLAVANONE HYDROXYFLAVANONE, 5-(RG) 6-METHOXYFLAVANONE 7-METHOXY-5-HYDROXYFLAVANONE HYDROXYFLAVANONE, 3',3'-HYDROXYFLAVANONE 6,2'',4''-TRIMETHOXYFLAVANONE DIHYDROOROXYLIN Hesperetin 6,2'-DIHYDROXYFLAVANONE 6,4'-DIMETHOXYFLAVANONE HYDROXYFLAVANONE, 2'-,2-HYDROXYFLAVANONE,2'-HYDROXYFLAVANONE,2'-Hydroxyflavanone,98% HYDROXYFLAVANONE, 4'-(RG),HYDROXYFLAVANONE,HYDROXYFLAVANONE, 4'-,4-HYDROXYFLAVANONE,4'-HYDROXYFLAVANONE 7-HYDROXYFLAVANONE 4',5,7,8-TETRAHYDROXYFLAVANONE 4H-NAPHTHO[1,2-B]PYRAN-4-ONE, 2,3-DIHYDRO-6-METHOXY-2-(3,4,5-TRIMETHOXYPHENYL)- HYDROXYFLAVANONE, 5-,5-HYDROXYFLAVANONE
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