Tetrahydropyran

Tetrahydropyran Basic information
Product Name:Tetrahydropyran
Synonyms:TETRAHYDROPYRAN;THP;OXACYCLOHEXANE;PENTAMETHYLENE OXIDE;2H-pyran,tetrahydro-;Etrahydropyran;UMOD;Uromodulin human
CAS:142-68-7
MF:C5H10O
MW:86.13
EINECS:205-552-8
Product Categories:Anhydrous Solvents;Solvent Bottles;Solvent by Application;Solvent Packaging Options;Solvents;Sure/Seal Bottles
Mol File:142-68-7.mol
Tetrahydropyran Structure
Tetrahydropyran Chemical Properties
Melting point -45 °C (lit.)
Boiling point 88 °C (lit.)
density 0.881 g/mL at 25 °C (lit.)
vapor density 3 (vs air)
refractive index n20/D 1.42(lit.)
Fp 4 °F
storage temp. Store below +30°C.
solubility >80.2g/l
form Liquid
color Clear colorless
Odorat 0.10?%?in?dipropylene glycol. pungent sweet ethereal
Water Solubility 80 g/L (25 ºC)
Merck 14,9217
BRN 102436
InChIKeyDHXVGJBLRPWPCS-UHFFFAOYSA-N
LogP0.950
CAS DataBase Reference142-68-7(CAS DataBase Reference)
NIST Chemistry Reference2H-Pyran, tetrahydro-(142-68-7)
EPA Substance Registry SystemTetrahydropyran (142-68-7)
Safety Information
Hazard Codes F,Xi,Xn
Risk Statements 11-36/37/38-9-19-52/53-22
Safety Statements 9-16-26-33-36-61
RIDADR UN 1993 3/PG 2
WGK Germany 3
TSCA Yes
HazardClass 3
PackingGroup II
HS Code 29321100
Hazardous Substances Data142-68-7(Hazardous Substances Data)
MSDS Information
ProviderLanguage
Pentamethylene oxide English
SigmaAldrich English
ACROS English
ALFA English
Tetrahydropyran Usage And Synthesis
Chemical Propertiescolorless to light yellow liquid
UsesIt is is an important raw material and intermediate used in Organic Synthesis, Pharmaceuticals, Agrochemicals and dyestuff. They are also used as important solvents, as chemical intermediate and as monomer for ring-opening polymerization.
DefinitionChEBI: A saturated organic heteromonocyclic parent that is cyclohexane in which one of the carbon atoms has been replaced by an oxygen atom.
Purification MethodsDry oxane with CaH2, then pass it through a column of silica gel to remove olefinic impurities and fractionally distil it. Free it from peroxides and moisture by refluxing with sodium, then distil it from LiAlH4. Alternatively, peroxides can be removed by treatment with aqueous ferrous sulfate and sodium bisulfate, followed by solid KOH, and fractional distillation from sodium. [Beilstein 17 H 12, 17 I 6, 17 II 18, 17 III/IV 51, 17/1 V 64.]
1,6-ANHYDRO-3,4-O-ISOPROPYLIDENE-2-TOSYL-B-D-GALACTOPYRANOSE 5-Bromo-4-chloro-3-indolyl-beta-D-galactoside DIGOXIN ETHYLENE OXIDE Tetramethylammonium hydroxide CYMARIN 4-Aminotetrahydropyran (1R)-(+)-CAMPHANIC ACID 2-Naphthyl-beta-D-galactopyranoside Tetrahydro-2H-pyran-4-carboxylic acid Digitoxin NITRIC OXIDE (+)-CAMPHANIC ACID CHLORIDE HECOGENIN ACETATE G-STROPHANTHIN NITROUS OXIDE Cyclopentene oxide Propylene oxide

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