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| | GALAXOLIDE Basic information |
| Product Name: | GALAXOLIDE | | Synonyms: | ABBALIDE;1,3,4,6,7,8-HEXAHYDRO-4,6,6,7,8,8-HEXAMETHYLCYCLOPENTA[G]-2-BENZOPYRAN;1,3,4,6,7,8-HEXAHYDRO-4,6,6,7,8,8-HEXAMETHYL-CYCLOPENTA-GAMMA-2-BENZOPYRAN;1,3,4,6,7,8-hexahydro-4,6,6,7,8,8-hexamethyl-cyclopenta(g)-2-benzopyra;GALAXOLIDE;GALAXOLIDE 50;GALAXOLIDE 50 BB;GALAXOLIDE 50 IPM | | CAS: | 1222-05-5 | | MF: | C18H26O | | MW: | 258.4 | | EINECS: | 214-946-9 | | Product Categories: | Aromatics;Detergents;Alphabetical Listings;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Flavors and Fragrances;G-H | | Mol File: | 1222-05-5.mol |  |
| | GALAXOLIDE Chemical Properties |
| Melting point | 57-58° | | Boiling point | 304 °C(lit.) | | density | 1.044 g/mL at 25 °C(lit.) | | vapor pressure | 0.073Pa at 25℃ | | refractive index | n20/D 1.5215(lit.) | | Fp | >230 °F | | storage temp. | Sealed in dry,Room Temperature | | form | clear liquid | | color | Colorless to Light yellow | | Odor | at 100.00 %. strong diffusive sweet floral musk | | Odor Type | musk | | Water Solubility | 1.65mg/L at 25℃ | | LogP | 5.3 at 25℃ | | CAS DataBase Reference | 1222-05-5(CAS DataBase Reference) | | EPA Substance Registry System | 1,3,4,6,7,8-Hexahydro-4,6,6,7,8,8-hexamethylcyclopenta[g]-2-benzopyran (1222-05-5) |
| | GALAXOLIDE Usage And Synthesis |
| Chemical Properties | Clear Colourless to Pale Yellow Oil | | Chemical Properties | 4,6,6,7,8,8-Hexamethyl-1,3,4,6,7,8-hexahydrocyclopenta[g]benzopyran is a viscous liquid with
a musk-like odor. It is one of the most frequently used synthetic, artificial musk
fragrances.The starting material for its synthesis is 1,1,2,3,3-pentamethylindane,
which is prepared by cycloaddition of tert-amylene to α-methylstyrene. The
pentamethylindane is hydroxyalkylated with propylene oxide in a Friedel–Crafts
reaction using aluminum chloride as a catalyst (analogous to the synthesis
of phenylethyl alcohol from benzene and ethylene oxide . Ring
closure of the resulting 1,1,2,3,3-pentamethyl-5-(β-hydroxyisopropyl)indane
is accomplished with paraformaldehyde and a lower aliphatic alcohol via the
acetal or with paraformaldehyde and a carboxylic acid anhydride via the
acylate.
The commercial product is diluted with solvents (e.g., diethyl phthalate, isopropyl
myristate, benzyl benzoate) to make it less viscous. It is alkali-stable and does not
discolor in light. Therefore, it is a popular ingredient of perfume compositions for
soaps, detergents, and cosmetics and is used in large amounts. | | Uses | Galaxolide is a polycyclic musk (PCM) used as a fragrance ingredient in perfumes, soaps, cosmetics and detergents. | | Definition | ChEBI: An organic heterotricyclic compound that is 1,3,4,6,7,8-hexahydrocyclopenta[g]isochromene substituted by methyl groups at positions 4, 6, 6, 7, 8 and 8 respectively. It is a synthetic musk used as a fragrance in cosmetics. | | General Description | 1,3,4,6,7,8-Hexahydro-4,6,6,7,8,8-hexamethylcyclopenta[g]-2-benzopyran is an isochromone with a strong musk odor, commonly used in fragrances. | | Flammability and Explosibility | Notclassified | | Trade name | Galaxolide® (IFF), Astromusk (Agan),Musk YingHai (YingHai). |
| | GALAXOLIDE Preparation Products And Raw materials |
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