| Uses | Aldolase from rabbit muscle has been used:
- in standard 1-phosphofructokinase from rabbit muscle (RPFK-1) assay
- as a standard in the characterization of metabolic enzymes from glaucomatous tissues
- in fructose 2,6-bisphosphate assay of human cell lines
|
| Uses | Aldolase is used to convert fructose 1,6-diphosphate to dihydroxyacetone phosphate and glyceraldehyde 3-phosphate. Aldolase, from rabbit muscle has been used for stereospecific deprotonation at DHAP C3 . Product A2714 is essentially sulfate-free and contains citrate buffer salts. |
| Definition | An enzyme present in muscle involved in glycogenolysis and anaerobic glycolysis. It catalyzes production of dihydroxyacetone phosphate and phosphoglyceric aldehyde from fructose-1,6-diphosphate. |
| General Description | Aldolase exists as three isoforms in rabbit, which includes type A from muscle, type B from liver and brain associated type C. Aldolases correspond to a molecular weight of 158 kDa and exists as tetramer. |
| Biochem/physiol Actions | Aldolase interaction with Wiskott-Aldrich syndrome protein (WASP) may modulate actin dynamics. It reverses the inhibition elicited by ascorbate on Muscle-type LDH (LDH-m4). |
