TYROSINASE

TYROSINASE Basic information
Product Name:TYROSINASE
Synonyms:Monophenol monooxidase;Monophenol oxidase;Phenol oxidase;Phenolase;Tyrosinase, Lyophilized powder;tyrosinase from mushroom;Tyrosinase mushroom;Tyrosinase from mushroom,Catechol Oxidase, Monophenol Monooxygenase, Monophenol, dihydroxyphenylalanine:oxygen oxidoreductase, Polyphenol Oxidase
CAS:9002-10-2
MF:NULL
MW:0
EINECS:232-653-4
Product Categories:
Mol File:Mol File
TYROSINASE Structure
TYROSINASE Chemical Properties
Melting point 89-94 °C
storage temp. -20°C
form lyophilized powder
CAS DataBase Reference9002-10-2
EPA Substance Registry SystemOxygenase, monophenol mono- (9002-10-2)
Safety Information
Hazard Codes Xn
Risk Statements 42
Safety Statements 22-24/25-45
WGK Germany 2
10-21
MSDS Information
TYROSINASE Usage And Synthesis
UsesTyrosinase activity has been assessed in a study that developed an alternative therapeutic agent for treating hyperpigmentation. Tyrosinase has also been used in a study to investigate the oculocutaneous albinism phenotype in the Pakistani population.
General DescriptionIsoelectric point (pI): 4.7-5
pH optimum is 6-7

Molecular weight: 128 kDa by sedimentation velocity diffusion; 133?kDa by light-scattering measurements, and 119.5 kDa by electrophoresis.

Tyrosinase is a copper-containing oxidase, which has activity for both catechols and cresol. It is responsible for browning reactions. The enzyme is reported to have two binding sites for aromatic substrates and a different binding site for oxygen-copper. The copper is probably Cu(I), with inactivation involving oxidation to Cu(II) ion.
Biochem/physiol ActionsConverts tyrosine to L-DOPA or tyramine to dopamine
TYROSINASE Preparation Products And Raw materials
Aluminum acetylacetonate METHYL ISOCYANOACETATE TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)EUROPIUM(III) N-BUTYLISOCYANIDE PHENYLSELENOL Tris(2,4-pentanedionato)chroMiuM(III) DICHLORO(ETHYLENEDIAMINE)PLATINUM(II) SALCOMINE 2,4-PENTANEDIONE, SILVER DERIVATIVE Tosylmethyl isocyanide COBALT(II) ACETYLACETONATE TYROSINASE FROM MUSHROOM BIOCHEMIKA, LYOPHILIZED, ≥2000 UNITS/MG Cupric acetylacetonate Ethyl isocyanoacetate TERT-BUTYL ISOCYANIDE Ferric acetylacetonate COBALT ETHYLENE DIAMINE CHLORIDE TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)DYSPROSIUM(III)

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