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| | 2-Fluoropyridine Chemical Properties |
| Boiling point | 126 °C/753 mmHg (lit.) | | density | 1.128 g/mL at 25 °C (lit.) | | refractive index | n20/D 1.466(lit.) | | Fp | 83 °F | | storage temp. | Inert atmosphere,2-8°C | | form | Liquid | | pka | -0.44(at 25℃) | | color | Clear colorless to light yellow | | Specific Gravity | 1.13 | | Water Solubility | Soluble in water. | | BRN | 1515 | | InChI | InChI=1S/C5H4FN/c6-5-3-1-2-4-7-5/h1-4H | | InChIKey | MTAODLNXWYIKSO-UHFFFAOYSA-N | | SMILES | C1(F)=NC=CC=C1 | | CAS DataBase Reference | 372-48-5(CAS DataBase Reference) | | NIST Chemistry Reference | 2-Fluoropyridine(372-48-5) |
| | 2-Fluoropyridine Usage And Synthesis |
| Synthesis | A rare example of fluorodenitration of a heterocyclic system was provided by 2-
nitropyridine, which was converted to 2-fluoropyridine.
 | | Chemical Properties | CLEAR COLOURLESS TO LIGHT YELLOW LIQUID | | Uses | 2-Fluoropyridine is a useful precursor of 2,3-disubstituted pyridines which is made by the possibility of metallation at C-3, together with the ready nucleophilic displacement of the activated fluorine. It can also react with thiophene to get 2-thiophen-2-yl-pyridine. It is used in the synthesis of aminopyridines. |
| | 2-Fluoropyridine Preparation Products And Raw materials |
| Raw materials | 2(5H)-Pyridinone(9CI)-->2-PYRIDYL TRIFLUOROMETHANESULFONATE-->Perfluoro-2-methyl-2-pentene-->2,4,6-TRIFLUOROPYRIDINE-->2,4-DIFLUORO-PYRIDINE-->2-Nitropyridine | | Preparation Products | 2-(5-BROMO-2-THIENYL)PYRIDINE-->2-Fluoro-3-pyridylboronic acid-->2,6-Difluoropyridine-->Pyrrolidine, 2,2,3,3,4,4,5,5-octafluoro-1-(trifluoromethyl)--->2-Pyridylacetonitrile-->3-Bromo-2-fluoropyridine-->2-Fluoro-3-iodopyridine-->2-Fluoro-3,6-diiodopyridine |
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