AYANIN

AYANIN Basic information
Product Name:AYANIN
Synonyms:QUERCETIN 3,7,4'-TRIMETHYL ETHER;AYANIN;2-(3-Hydroxy-4-methoxyphenyl)-3,7-dimethoxy-5-hydroxy-4H-1-benzopyran-4-one;3',5-Dihydroxy-3,4',7-trimethoxyflavone;3,7,4'-Tri-O-methylquercetin;5-Hydroxy-2-(3-hydroxy-4-methoxyphenyl)-3,7-dimethoxy-4H-1-benzopyran-4-one;Quercetin 3,4',7-trimethyl ether;4H-1-Benzopyran-4-one,5-hydroxy-2-(3-hydroxy-4-Methoxyphenyl)-3,7-diMethoxy-
CAS:572-32-7
MF:C18H16O7
MW:344.32
EINECS:
Product Categories:
Mol File:572-32-7.mol
AYANIN Structure
AYANIN Chemical Properties
Melting point 173℃
Boiling point 600.8±55.0 °C(Predicted)
density 1.45±0.1 g/cm3(Predicted)
storage temp. 4°C, protect from light
pka6.15±0.40(Predicted)
Safety Information
MSDS Information
AYANIN Usage And Synthesis
UsesAyanin is a bioflavonoid isolated from Croton schiedeanus Schlecht. Ayanin is a non-selective phosphodiesterase inhibitor.
DefinitionChEBI: 3',5-dihydroxy-3,4',7-trimethoxyflavone is a trimethoxyflavone that is quercetin in which the hydroxy groups at positions 3, 4' and 7 have been replaced by methoxy groups. It has a role as a plant metabolite. It is a dihydroxyflavone and a trimethoxyflavone. It is functionally related to a quercetin. It is a conjugate acid of a 3',5-dihydroxy-3,4',7-trimethoxyflavone(1-).
Biological ActivityAyanin is a biologically active flavonoid isolated from Croton schiedeanus Schlecht. Ayanin is a non-selective phosphodiesterase (phosphodiesterase1-4) inhibitor, which can be used in the study of respiratory diseases, such as allergic asthma.
in vitro

Ayanin inhibits interleukin (IL)-4 production from purified basophils with an IC 50 value of 2.2 μM.

target

PDE2A

PDE4

2-(3,4-Dihydroxyphenyl)-8-(2-O-beta-L-galactopyranosyl-beta-D-glucopyranosyl)-5,7-dihydroxy-4H-1-Benzopyran-4-one Naringenin 7-O-β-D-Glucuronide (Mixture of Diastereomers) Quercetin-7-O-β-D-glucopyranoside hydroxygenkwanin Naringenin PONCIRIN MEDICAGOL 4',5-DIHYDROXY-7-METHOXYFLAVONE MOSLOFLAVONE GARDENIN B 3',4',7-TRIMETHOXYFLAVONE

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