ChemicalBook Product Catalog Pharmaceutical intermediates Heterocyclic compound Quinoline compounds 6-Fluoroquinaldine

6-Fluoroquinaldine

6-Fluoroquinaldine Basic information
Product Name:6-Fluoroquinaldine
Synonyms:6-Fluoro-2-methylquinoline, 98+%;6-Fluoro-2-methyl-1-azanaphthalene;AKOS 1002;6-FLUORO-2-METHYLQUINOLINE;6-FLUOROQUINALDINE;6-Fluoro-2-methylquinoline 97%;6-Fluoro-2-methylquinoline97%;2-METHYL-6-FLUOROQUINOLINE
CAS:1128-61-6
MF:C10H8FN
MW:161.18
EINECS:214-439-2
Product Categories:Aromatics Compounds;Quinolines, Quinazolines and derivatives;Quinoline&Isoquinoline;Alkylquinolines;Haloquinolines;Quinolines;Aromatics;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Building Blocks;Heterocyclic Building Blocks
Mol File:1128-61-6.mol
6-Fluoroquinaldine Structure
6-Fluoroquinaldine Chemical Properties
Melting point 49-53 °C (lit.)
Boiling point 99 °C / 3mmHg
density 1.1465 (estimate)
Fp >230 °F
storage temp. Inert atmosphere,Room Temperature
solubility Soluble in Chloroform.
pka5.16±0.43(Predicted)
form powder to crystal
color White to Almost white
BRN 1281677
CAS DataBase Reference1128-61-6(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 38-41-36/37/38
Safety Statements 26-37/39-36
WGK Germany 3
Hazard Note Irritant
HS Code 29334990
MSDS Information
ProviderLanguage
SigmaAldrich English
ACROS English
ALFA English
6-Fluoroquinaldine Usage And Synthesis
Chemical Propertiesbrown powder or granules
UsesMetal-free transfer hydrogenation of 6-fluoro-2-methylquinoline by employing several chiral Br?nsted acid catalysts was carried out in combination with dihydropyridines as the hydride source in asymmetric metal-free synthesis of fluoroquinolones by organocatalytic hydrogenation. Hydrogenation product of 6-fluoro-2-methylquinoline is the key intermediate of the antibacterial agent.
UsesQuinoline derivative as a highly potent thrombin receptor antagonist
Brequinar 4-Quinolinecarboxylic acid, 2-(10-(3-(dimethylamino)propyl)-10H-phenot hiazin-2-yl)-6-fluoro-,ethyl ester, monohydrochloride 4-CHLORO-6-FLUOROQUINALDINE 6,8-difluoro-2-methylquinolin-4-ol 6-Fluoroquinaldine 4-CHLORO-6-FLUORO-2-TRICHLOROMETHYLQUINOLINE 6-FLUORO-2-METHYLQUINOLINEHYDROCHLORIDE1/2ZINCCHLORIDE 2-FLUORO-7,8,9,10-TETRAHYDRO-6H-CYCLOHEPTA[B]QUINOLINE-11-CARBOXYLIC ACID 6-FLUORO-2-(TRIBROMOMETHYL)QUINOLINE AKOS 92510 AURORA KA-4991 6-FLUORO-2-PHENYLQUINOLINE-4-CARBOXYLIC ACID 6-FLUORO-4-HYDROXY-2-METHYLQUINOLINE 6-FLUORO-4-HYDROXY-2-(TRIFLUOROMETHYL)QUINOLINE 4-CHLORO-6-FLUORO-2-(TRIFLUOROMETHYL)QUINOLINE 7-FLUORO-1,2,3,4-TETRAHYDRO-ACRIDINE-9-CARBOXYLIC ACID AURORA KA-4990 6-FLUORO-4-HYDRAZINO-2-METHYLQUINOLINE
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