2-Anilinoethanol

2-Anilinoethanol Basic information

Product Name:	2-Anilinoethanol
Synonyms:	2-anilino-ethano;Aniline, N-(2-hydroxyethyl)-;Aniline, N-(beta-hydroxyethyl)-;Benzenamine, N-(2-hydroxyethyl)-;Emery 5700;emery5700;Ethanol, 2-anilino-;N-(2-Hydroxyethyl)aniline 2-(Phenylamino)ethanol N-Phenylethanolamine
CAS:	122-98-5
MF:	C8H11NO
MW:	137.18
EINECS:	204-588-1
Product Categories:	Intermediates of Dyes and Pigments;Amino Alcohols;Building Blocks;Chemical Synthesis;Organic Building Blocks;Oxygen Compounds;Hydroxyethylamines;122-98-5
Mol File:	122-98-5.mol

2-Anilinoethanol Chemical Properties

Melting point	-30 °C
Boiling point	150-152 °C10 mm Hg(lit.)
density	1.094 g/mL at 25 °C(lit.)
vapor density	>1 (vs air)
vapor pressure	<0.01 mm Hg ( 20 °C)
refractive index	n20/D 1.578(lit.)
Fp	>230 °F
storage temp.	Store below +30°C.
solubility	4.5g/l
pka	14.39±0.10(Predicted)
form	clear liquid
color	Colorless to Red to Green
PH	10.2 (10g/l, H2O, 20℃)
explosive limit	1-6.8%(V)
Water Solubility	53 g/L (20 ºC)
BRN	774672
InChIKey	MWGATWIBSKHFMR-UHFFFAOYSA-N
LogP	0.9 at 23℃
CAS DataBase Reference	122-98-5(CAS DataBase Reference)
NIST Chemistry Reference	Ethanol, 2-(phenylamino)-(122-98-5)
EPA Substance Registry System	Ethanol, 2-(phenylamino)- (122-98-5)

Safety Information

Hazard Codes	T
Risk Statements	24-41-48/20/21/22-36-R36-R24
Safety Statements	26-36/37/39-45-28A-S45-S36/37/39-S28A-S26
RIDADR	UN 2810 6.1/PG 2
WGK Germany	1
RTECS	KJ7175000
Autoignition Temperature	410 °C DIN 51794
TSCA	Yes
HazardClass	6.1
PackingGroup	II
HS Code	29221990
Toxicity	LD50 orally in Rabbit: 2230 mg/kg LD50 dermal Rabbit 68 mg/kg

MSDS Information

2-Anilinoethanol Usage And Synthesis

Chemical Properties	CLEAR YELLOW TO BROWN LIQUID
Uses	N-Phenylethanolamine is used as an intermediate for dyes and other organic compounds. Further, it is used as a substrate for human olfactory uridine 5'-diphospho-glucuronosyltransferase.
Uses	N-(2-Hydroxyethyl)aniline was employed as substrate for human olfactory UDP-glucuronosyltransferase.
Definition	ChEBI: 2-Anilinoethanol is an aralkylamine.
Synthesis Reference(s)	Journal of Medicinal Chemistry, 11, p. 87, 1968 DOI: 10.1021/jm00307a019 Journal of the American Chemical Society, 74, p. 5514, 1952 Tetrahedron Letters, 10, p. 4555, 1969 DOI: 10.1017/S0009838800024678
Synthesis Reference(s)	Synthetic Communications, 24, p. 1415, 1994 DOI: 10.1080/00397919408011745
Flammability and Explosibility	Notclassified
Safety Profile	Poison by skin contact, intraperitoneal, and intravenous routes. Moderately toxic by ingestion. A skin and severe eye irritant. Combustible when exposed to heat or flame. To fight fire, use dry chemical, water mist. When heated to decomposition it emits toxic fumes of NOx.

2-Anilinoethanol Preparation Products And Raw materials

Raw materials	Aniline-->ETHYLENE OXIDE-->2-Phenoxyethylamine-->DIPHENYLIODONIUM TRIFLUOROMETHANESULFONATE-->3-PHENYL-2-OXAZOLIDINONE
Preparation Products	1H-ISOINDOLE-1,3(2H)-DIONE, 2-[(2R)-2-HYDROXY-3-[[4-(3-OXO-4-MORPHOLINYL)PHENYL]AMINO]PROPYL]--->N-(2-Trimethylsiloxyethyl)aniline-->(R,E)-2-(benzo[d][1,3]dioxol-5-ylMethyleneaMino)-2-phenylethanol-->N-Ethyl-N-hydroxyethylaniline-->4,5-dichlorothiophene-2-carbonyl chloride

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