6-Aminopenicillanic acid

6-Aminopenicillanic acid Basic information

Product Name:	6-Aminopenicillanic acid
Synonyms:	6-AMINO-3,3-DIMETHYL-7-OXO-4-THIA-1-AZABICYCLO[3.2.0]HEPTANE-2-CARBOXYLIC ACID;(+)-6-AMINOPENICILLANIC ACID;6-AMINOPENICILLANIC ACID;6-AMINO PENICILLINIC ACID;7-AMINO-3,3-DIMETHYL-6-OXO-2-THIA-5-AZABICYCLO[3.2.0]HEPTANE-4-CARBOXYLIC ACID;(25,5R,6R)-6-AMINO-3,3-DIMETHYL-7-OXO-4-THIA-1-AZABICYCLO[3.2.0]HEPTANE-2-CARBOXYLIC ACID;(2S,5R,6R)-6-AMINO-3,3-DIMETHYL-7-OXO-4-THIA-1-AZABICYCLO-[3.2.0]HEPTANE-2-CARBOXYLIC ACID;aminopenicillanicacid
CAS:	551-16-6
MF:	C8H12N2O3S
MW:	216.26
EINECS:	208-993-4
Product Categories:	Chemical Intermediate;Antibiotics for Research and Experimental Use;beta-Lactams (Antibiotics for Research and Experimental Use);Biochemistry;Used as pharmaceutical intermediates;API;Organic acids
Mol File:	551-16-6.mol

6-Aminopenicillanic acid Chemical Properties

Melting point	198-200 °C (dec.)(lit.)
alpha	276.3 º (c=1.2, 0.1N HCl 22 ºC)
Boiling point	460.2±45.0 °C(Predicted)
density	1.3418 (rough estimate)
refractive index	1.6300 (estimate)
storage temp.	2-8°C
solubility	2.46g/l
form	Fine Powder
pka	pKa 2.3 (Uncertain)
color	White to cream
PH	3.4 (100g/l, H2O)
optical activity	[α]22/D +276.3°, c = 1.2 in 0.1 M HCl
Water Solubility	Soluble in water and hydrochoric acid.
Merck	14,458
BRN	15080
Stability:	Light sensitive
InChIKey	NGHVIOIJCVXTGV-SDKNWNMFSA-N
LogP	-3.87 at 22.5℃
CAS DataBase Reference	551-16-6(CAS DataBase Reference)
EPA Substance Registry System	6-Aminopenicillanic acid (551-16-6)

Safety Information

MSDS Information

6-Aminopenicillanic acid Usage And Synthesis

Chemical Properties	WHITE TO CREAM FINE POWDER
Uses	6-Aminopenicillanic acid is the basic unit in penicillin?s, which is obtained from the fermentation brew of the Penicillium mold. It acts as a starting material for the preparation of many semisynthetic penicillins. Further, it serves as apharmaceutical intermediate. In addition to this, it is used in antibiotics research and experimental application.
Uses	(+)-6-Aminopenicillanic Acid is the core structure in penicillins, obtained from the fermentation brew of the Penicillium mold. (+)-6-Aminopenicillanic Acid is used as the main starting block for the preparation of numerous semisynthetic penicillins.
Definition	ChEBI: A penicillanic acid compound having a (6R)-amino substituent. The active nucleus common to all penicillins, it may be substituted at the 6-amino position to form the semisynthetic penicillins, resulting in a variety of antibacterial and ph rmacologic characteristics.
General Description	Chemical structure: ?-lactam
Flammability and Explosibility	Nonflammable
Safety Profile	Questionable carcinogen with experimental tumorigenic data. When heated to decomposition it emits very toxic fumes of NOx and SOx.
Purification Methods	This acid crystallises from water. [Kleppe & Stroninger J Biol Chem 254 4856 1979,Beilstein 27 III/IV 2858.]

6-Aminopenicillanic acid Preparation Products And Raw materials

Raw materials

Preparation Products

Login