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| | 2,6-Dichloropyridine Basic information |
| Product Name: | 2,6-Dichloropyridine | | Synonyms: | AKOS BBS-00004314;26DCLPY;2,6-DICHLOROPYRIDINE;AURORA KA-6495;2,6-dichloro-pyridin;2,6-Dichloropyridine,97%;Pyridine, 2,6-dichloro-;2,6-DichL | | CAS: | 2402-78-0 | | MF: | C5H3Cl2N | | MW: | 147.99 | | EINECS: | 219-282-3 | | Product Categories: | alkyl chloride;Chlorinated heterocyclic series;C5 to C6;Building Blocks;C5;Pharmaceutical Intermediates;Chloropyridines;Halopyridines;C5Heterocyclic Building Blocks;Halogenated Heterocycles;Heterocyclic Building Blocks;Chemical Synthesis;Halogenated Heterocycles;Heterocyclic Building Blocks;blocks;Pyridines;Pyridines, Pyrimidines, Purines and Pteredines;Pyridine;Pyridines derivates;bc0001 | | Mol File: | 2402-78-0.mol |  |
| | 2,6-Dichloropyridine Chemical Properties |
| Melting point | 83-86 °C (lit.) | | Boiling point | 211 °C | | density | 1.5159 (rough estimate) | | refractive index | 1.5500 (estimate) | | Fp | 110°C | | storage temp. | Inert atmosphere,2-8°C | | solubility | methanol: 50 mg/mL, clear | | form | Crystalline Powder | | pka | -3.02±0.10(Predicted) | | color | White to pink or grayish-white | | PH | 6-7 (H2O, 20℃)(saturated solution) | | Water Solubility | <1 g/L (20 ºC) | | BRN | 108664 | | InChIKey | FILKGCRCWDMBKA-UHFFFAOYSA-N | | CAS DataBase Reference | 2402-78-0(CAS DataBase Reference) | | NIST Chemistry Reference | Pyridine, 2,6-dichloro-(2402-78-0) | | EPA Substance Registry System | 2,6-Dichloropyridine (2402-78-0) |
| Hazard Codes | T,Xn | | Risk Statements | 25-36/37/38-22-23/24/25 | | Safety Statements | 36/37/39-45-37/39-26-36 | | RIDADR | UN 2811 6.1/PG 2 | | WGK Germany | 3 | | RTECS | US8400000 | | Hazard Note | Toxic | | TSCA | Yes | | HazardClass | 6.1 | | PackingGroup | III | | HS Code | 29333999 | | Toxicity | mouse,LD50,intraperitoneal,115mg/kg (115mg/kg),BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)LIVER: FATTY LIVER DEGERATIONBEHAVIORAL: ANTIPSYCHOTIC,Toxicology and Applied Pharmacology. Vol. 11, Pg. 361, 1967. |
| | 2,6-Dichloropyridine Usage And Synthesis |
| Chemical Properties | White to light yellow solid | | Uses | 2,6-Dichloropyridine is used in the preparation of triazolo and imidazo potassium channel antagonists as antiarrythmic agents. | | Purification Methods | It crystallises from EtOH. [Beilstein 20/5 V 416.] |
| | 2,6-Dichloropyridine Preparation Products And Raw materials |
| Raw materials | Pyridine-->2-CHLORO-6-FLUOROPYRIDINE | | Preparation Products | 4-Amino-2,6-dichloropyridine-->3-Amino-6-chloropyridine-2-carboxylic acid-->2-Amino-6-methoxypyridine-->2,4,6-Trichloropyridine-->2-Amino-6-chloro-3-nitropyridine-->6-Chloropyridn-2-ol-->2,6-DIETHYNYLPYRIDINE-->2,6-Dichloro-1-fluoropyridinium triflate-->2,6-Di(1-pyrazolyl)pyridine-->4,6-Dichloropyrido[3,2-d]pyrimidine-->2,6-DICHLORO-4-METHOXY-PYRIDINE-->2,6-DICHLOROPYRIDINE-3,4-DIAMINE-->2,6-Dichloroisonicotinonitrile-->2-Amino-6-methoxy-3-nitropyridine-->2-CHLORO-9H-PYRIDO[2,3-B]INDOLE-->2,6-DICHLORO-3-NITRO-4-AMINOPYRIDINE-->3-Chloropyridine |
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