1-Cyclohexylpiperazine

1-Cyclohexylpiperazine Basic information
Product Name:1-Cyclohexylpiperazine
Synonyms:N-Cyclohexylpiperazine;BUTTPARK 82\06-06;1-CYCLOHEXYL-PIPERAZINE >98%;1-CYCLOHEXYLPIPERAZINE 98%;1-Cyclohexylpiperizine;Piperazine, 1-cyclohexyl-;AKOS BBS-00003612;1-Cyclohexylpiperazine ,97%
CAS:17766-28-8
MF:C10H20N2
MW:168.28
EINECS:241-750-0
Product Categories:Building Blocks;Heterocyclic Building Blocks;Amines and Anilines;Piperazines;Intermediate
Mol File:17766-28-8.mol
1-Cyclohexylpiperazine Structure
1-Cyclohexylpiperazine Chemical Properties
Melting point 28-32 °C
Boiling point 287.25°C (rough estimate)
density 0.9725 (rough estimate)
refractive index 1.6011
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility Chloroform (Slightly), Methanol (Slightly)
form Low Melting Solid
pka9.25±0.10(Predicted)
color Yellow-brownish
BRN 106845
InChIKeyXPDSXKIDJNKIQY-UHFFFAOYSA-N
CAS DataBase Reference17766-28-8(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 24/25-26
WGK Germany 3
Hazard Note Irritant
HS Code 29335990
MSDS Information
ProviderLanguage
1-Cyclohexylpiperazine English
ACROS English
1-Cyclohexylpiperazine Usage And Synthesis
Chemical Propertiesyellow-brownish low melting solid
Uses1-Cyclohexylpiperazine is an σ1 and σ2 receptor ligands with diagnostic and therapeutic potentials.
Synthesis Reference(s)Tetrahedron Letters, 35, p. 7331, 1994 DOI: 10.1016/0040-4039(94)85306-1
1-Cyclohexylpiperazine Preparation Products And Raw materials
Raw materialsEthanol-->Sodium hydroxide-->Dichloromethane-->Potassium carbonate-->Acetonitrile-->Piperazine-->Potassium iodide-->Bromocyclohexane
Cyclohexanecarboxylic acid 1-(4-METHYL-CYCLOHEXYL)-PIPERAZINE 1-Cyclohexylpiperazine Pipecuronium bromide 3-(4-CYCLOHEXYL-PIPERAZIN-1-YL)-PROPIONIC ACID Cyclohexanecarboxaldehyde AKOS B017837 3-(4-CYCLOHEXYLPIPERAZIN-1-YL)-1-(4-FLUOROPHENYL)-1H-PYRROLE-2,5-DIONE (1-alpha,2-beta,6-beta)-2-(4-(3-Methoxyphenyl)-1-piperazinyl)-6-phenox ycyclohexanol 2HCl Allyl cyclohexylpropionate Bicyclo(3.3.1)nonan-9-ol, 2-(4-(4-fluorophenyl)-1-piperazinyl)-9-pheny l-, monohydrochloride Piperazinium, 1-cyclohexyl-1,4-dimethyl-4-(alpha-methylphenethyl)-, di bromide 1,1-Dimethyl-4-(1-phenylcyclohexyl)piperazinium, iodide 1-(1-Piperazinyl)adamantane dihydrochloride 1-Piperazinecarboxamide, 4-cyclohexyl-N-((dimethylamino)carbonyl)-N-me thyl-, monohydrochloride (R)-1-CYCLOHEXYL-3-METHYL-PIPERAZINE Isocyanatocyclohexane Molasses

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