Flutriafol

Flutriafol Basic information
Product Name:Flutriafol
Synonyms:FLUTRIAFOL;CINCIT(R);ATOUT(R);(RS)-2,4-difluoro-α-(1H-1,2,4-triazol-1-ylmethyl)benzhydryl alcohol;FLUTRIAFOL SOLUTION 100 NG/MYL IN ACETON ITRILE, PESTANAL;Flutriafol TC;1H-1,2,4-Triazole-1-ethanol, .alpha.-(2-fluorophenyl)-.alpha.-(4-fluorophenyl)-;flutriafol (ansi,bsi,iso)
CAS:76674-21-0
MF:C16H13F2N3O
MW:301.29
EINECS:
Product Categories:Agriculture;Alpha sort;ConazolesPesticides&Metabolites;E-GAlphabetic;F;FA - FL;Fungicides;Pesticides
Mol File:76674-21-0.mol
Flutriafol Structure
Flutriafol Chemical Properties
Melting point 130°
Boiling point 506.5±60.0 °C(Predicted)
density 1.3015 (estimate)
vapor pressure 7.1 x l0-9 Pa (20 °C)
Fp 2 °C
storage temp. 0-6°C
solubility Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
pka11.60±0.29(Predicted)
Water Solubility 130 mg l-1 (pH 7,20 °C)
form neat
color White to Off-White
Merck 13,4240
BRN 8155287
Stability:Stable. Incompatible with strong oxidizing agents.
InChIKeyJWUCHKBSVLQQCO-UHFFFAOYSA-N
LogP2.290
CAS DataBase Reference76674-21-0(CAS DataBase Reference)
NIST Chemistry ReferenceFlutriafol(76674-21-0)
EPA Substance Registry SystemFlutriafol (76674-21-0)
Safety Information
Hazard Codes Xn,F
Risk Statements 22-36-20/21/22-11
Safety Statements 22-24/25-36-26
RIDADR UN 1648 3/PG 2
WGK Germany 3
RTECS XZ4825000
HS Code 29339900
ToxicityLD50 male, female rats (mg/kg): 1140, 1480 orally; rats, rabbits: >1000, >2000 percutaneously (Skidmore)
MSDS Information
Flutriafol Usage And Synthesis
Chemical Propertiessolid
UsesAgricultural fungicide.
UsesFlutriafol is used to control a wide variety of leaf and ear diseases in cereals. It is also used in seed treatment formulations to control the major soil-borne and seed-borne diseases of cereals.
UsesFlutriafol is a systemic fungicide of the triazole class. Flutriafol has broad spectrum fungicidal activity and is used to control effectively cereal powdery mildew, cloud disease, leaf spot disease a nd rust disease.
DefinitionChEBI: 1-(2-fluorophenyl)-1-(4-fluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanol is a tertiary alcohol that is ethanol in which one of the hydrogens at position 1 is replaced by an p-fluorophenyl group, the other hydrogen at position 1 is replaced by a p-fluorophenyl group, and one of the hydrogens at position 2 is replaced by a 1H-1,2,4-triazol-1-yl group. It is a member of triazoles, a tertiary alcohol and a member of monofluorobenzenes.
Metabolic pathwayFlutriafol is stable to hydrolysis and to light and it is persistent in soils. In crops, the metabolites identified were derivatives of triazole.
DegradationFlutriafol, 1, is stable to hydrolysis at pH 5,7 and 9 in water at 50 °C over a period of 30 days in the dark.
[14C-friazole]Flutriafoaln d [14C-carbinol]flutriafol were applied at a rate equivalent to 94 g ai ha-1 to samples of dry sandy loam soil distributed as a thin layer on 10 cm diameter glass plates. Samples were exposed to natural sunlight for 30 days or to alternating periods of 'black light' and darkness for 7 days. Recovery was 60-47% of applied radioactivity after 7 days artificial illumination and 74-85% after exposure to natural sunlight. All degradation products accounted for <5 %of the total applied radioactivity (PSD, 1996).
Flutriafol Preparation Products And Raw materials
Preparation Products2-Fluorobenzoic acid
1,1-Diphenyl-2-(1H-1,2,4-triazol-1-yl)ethanol 1,2,4-Triazole 2-(2-FLUOROPHENYL)-2-(4-FLUOROPHENYL)OXIRANE [FOR FLUTRIAFOL] 1-(2-HYDROXYETHYL)-1,2,4-TRIAZOLE 1-(2-Fluorophenyl)ethanol Phenylacetone 1-PROPYL-1,2,4-TRIAZOLE 2-(4-FLUOROPHENYL)-2-PROPANOL 1-AMINO-2-PHENYL-PROPAN-2-OL 2-AMINO-1-(2-FLUORO-PHENYL)-ETHANOL 4-FLUOROBENZHYDROL α-(Aminomethyl)-4-fluorobenzyl alcohol 1-(4-Fluorophenyl)ethanol FLUTRIAFOL SOLUTION 100UG/ML IN ACETONITRILE 1ML Ethyl acetate 4-Fluorophenethylamine 2-FLUOROPHENETHYLAMINE FLUTRIAFOL SOLUTION 100UG/ML IN TOLUENE 1ML

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