LY2811376

LY2811376 Basic information
Product Name:LY2811376
Synonyms:LY2811376;(4S)-4-[2,4-Difluoro-5-(5-pyrimidinyl)phenyl]-5,6-dihydro-4-methyl-4H-1,3-thiazin-2-amine;LY 2811376,(4S)-4-[2,4-Difluoro-5-(5-pyriMidinyl)phenyl]-5,6-dihydro-4-Methyl-4H-1,3-thiazin-2-aMine;CS-1893;LY 2811376;LY-2811376;(S)-4-(2,4-difluoro-5-(pyriMidin-5-yl)phenyl)-4-Methyl-5,6-dihydro-4H-1,3-thiazin-2-aMine;(4S)-4-(2,4-difluoro-5-pyriMidin-5-ylphenyl)-4-Methyl-5,6-dihydro-1,3-thiazin-2-aMine;N-Hydroxy-4-[(1,2,3,4-tetrahydro-2-methyl-5H-pyrido[4,3-b]indol-5-yl)methyl]benzamide hydrochloride Tubastatin A HCl LY2811376
CAS:1194044-20-6
MF:C15H14F2N4S
MW:320.36
EINECS:
Product Categories:Inhibitor;Inhibitors
Mol File:1194044-20-6.mol
LY2811376 Structure
LY2811376 Chemical Properties
Boiling point 486.5±55.0 °C(Predicted)
density 1.42
storage temp. Store at -20°C
solubility Soluble in DMSO
form crystalline solid
pka5.60±0.40(Predicted)
Safety Information
MSDS Information
LY2811376 Usage And Synthesis
UsesLY 281137 is a compound capable of the decrease in β-amyloid peptide (Aβ) associated with the cleavage of amyloid precursor protein (APP) by β-secretase (BACE) and γ-secretase. This decrease is important as its hypothesized that the build up of (Aβ) in the brain is a primary cause of neurodegeneration and Alzheimer’s progression.
LY2811376 Preparation Products And Raw materials
LY 2157299 Abemaciclib mesylate (LY2835219) Rapamycin LY 294002 HYDROCHLORIDE Afatinib LY-2608204 LY 2874455 LY2090314 LY 310762 LY411575 DIFLUOROIODOMETHANE Avagacestat (BMS-708163) Temsirolimus LY-364947 LY2409881 trihydrochloride LY2584702 LY-2584702 (tosylate salt) Saracatinib

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