ChemicalBook Product Catalog Organic Chemistry Hydrocarbons and derivatives Hydrocarbon halides 2,5-Difluorobenzyl bromide

2,5-Difluorobenzyl bromide

2,5-Difluorobenzyl bromide Basic information
Product Name:2,5-Difluorobenzyl bromide
Synonyms:ALPHA-BROMO-2,5-DIFLUOROTOLUENE;2,5-DIFLUOROBENZYL BROMIDE;2-(Bromomethyl)-1,4-difluorobenzene;Benzene, 2-(bromomethyl)-1,4-difluoro-;TIMTEC-BB SBB006680;à-bromo-2,5-difluorotoluene;α-bromo-2,5-difluorotoluene;2,5-Difluorobenzyl bromide 98%
CAS:85117-99-3
MF:C7H5BrF2
MW:207.02
EINECS:285-651-0
Product Categories:Benzhydrols, Benzyl & Special Alcohols;Fluoro-contained benzyl bromide series;Miscellaneous;Fluorinated benzene series;Fluorine series
Mol File:85117-99-3.mol
2,5-Difluorobenzyl bromide Structure
2,5-Difluorobenzyl bromide Chemical Properties
Boiling point 28 °C
density 1.609 g/mL at 25 °C(lit.)
refractive index n20/D 1.526(lit.)
Fp 60 °F
storage temp. Inert atmosphere,2-8°C
form clear liquid
Specific Gravity1.6090
color Colorless to Light orange to Yellow
BRN 7089248
CAS DataBase Reference85117-99-3(CAS DataBase Reference)
NIST Chemistry Reference2,5-Difluorobenzyl bromide(85117-99-3)
Safety Information
Hazard Codes F,C,Xi
Risk Statements 11-34-22-36
Safety Statements 26-36/37/39-45-16
RIDADR UN 2924 3/PG 2
WGK Germany 3
Hazard Note Corrosive/Lachrymatory
HazardClass 8
PackingGroup III
HS Code 29039990
MSDS Information
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2,5-Difluorobenzyl bromide Usage And Synthesis
Chemical PropertiesCLEAR YELLOW LIQUID
Uses2,5-Difluorobenzyl bromide has been used in the synthesis of:
  • novel series of 4-aryl, 4-phenylsulfonyl cyclohexananone-derived γ-secretase inhibitors, for the potential treatment of Alzheimer′s disease
  • sulfonamide, amide and acyclic amine derivatives
2,5-Difluorobenzyl bromide Preparation Products And Raw materials
Preparation Productscis-4-[(4-Chlorophenyl)sulfonyl]-4-(2,5-difluorophenyl)cyclohexanepropanoic acid-->4-[(2,5-difluorophenyl)methoxy]benzaldehyde-->(4-chlorophenyl)(2,5-difluorobenzyl)sulfane
2,5-DIFLUORO-4-NITROBENZYL BROMIDE 2,5-Difluorobenzyl bromide Ethyl bromodifluoroacetate alpha-Chloro-o-fluorotoluene DIBROMOMETHYLPENTAFLUOROBENZENE BRETYLIUM TOSYLATE Clidinium bromide 2,4,5-Trifluorobenzyl bromide Sodium bromate Benzyl bromide 4-Fluorobenzyl chloride Ethidium bromide 4-METHYL-2,3,5,6-TETRAFLUOROBENZYL BROMIDE 1,2-Difluorobenzene Methyl bromide PENTAFLUOROBENZYL BROMIDE 2,3,5,6-TETRAFLUOROBENZYL BROMIDE BROMOTRIFLUOROMETHANE
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