ChemicalBook Product Catalog Organic Chemistry Hydrocarbons and derivatives 4-[1-(4,5-DIHYDRO-4,4-DIMETHYL-2-OXAZOLYL)-1-METHYLETHYL]-BENZENEETHANOL

4-[1-(4,5-DIHYDRO-4,4-DIMETHYL-2-OXAZOLYL)-1-METHYLETHYL]-BENZENEETHANOL

4-[1-(4,5-DIHYDRO-4,4-DIMETHYL-2-OXAZOLYL)-1-METHYLETHYL]-BENZENEETHANOL Basic information
Product Name:4-[1-(4,5-DIHYDRO-4,4-DIMETHYL-2-OXAZOLYL)-1-METHYLETHYL]-BENZENEETHANOL
Synonyms:4-[1-(4,5-DIHYDRO-4,4-DIMETHYL-2-OXAZOLYL)-1-METHYLETHYL]-BENZENEETHANOL;2-(4-(2-(4,4-diMethyl-4,5-dihydrooxazol-2-yl)propan-2-yl)phenyl)ethanol;4-[1-(4,5-DIHYDRO-4,4-DIMETHYL-2-OXAZOLYL)-1-METHYLETHYL]-BENZENEETHANO;2-[4-[1-(4,4-diMethyl-5H-oxazol-2-yl)-1-Methyl-ethyl]phenyl]ethanol;Bilastine Intermediate 2;2-(4-(2-(4,4-dimethyl-4,5-dihydrooxazol-2-yl)propan-2-yl)phenyl)ethan-1-ol;2-{4-[2-(4,4-Dimethyl-4,5-dihydro-1,3-oxazol-2-yl)-2-propanyl]phenyl}ethanol;Bilastine impurity B
CAS:361382-26-5
MF:C16H23NO2
MW:261.36
EINECS:
Product Categories:
Mol File:361382-26-5.mol
4-[1-(4,5-DIHYDRO-4,4-DIMETHYL-2-OXAZOLYL)-1-METHYLETHYL]-BENZENEETHANOL Structure
4-[1-(4,5-DIHYDRO-4,4-DIMETHYL-2-OXAZOLYL)-1-METHYLETHYL]-BENZENEETHANOL Chemical Properties
Boiling point 373.4±30.0 °C(Predicted)
density 1.05±0.1 g/cm3(Predicted)
solubility soluble in Dichloromethane;
pka14.88±0.10(Predicted)
form Oil
color Yellow
Safety Information
MSDS Information
4-[1-(4,5-DIHYDRO-4,4-DIMETHYL-2-OXAZOLYL)-1-METHYLETHYL]-BENZENEETHANOL Usage And Synthesis
Uses4-[1-(4,5-Dihydro-4,4-dimethyl-2-oxazolyl)-1-methylethyl]benzeneethanol-d6 is an intermediate used in the synthesis of Bilastine-d6 (B385002), which is labelled Bilastine. It is a novel, nonsedating H1-antihistamine developed for symptomatic treatment of allergic rhinitis and chronic idiopathic urticaria.
4-[1-(4,5-DIHYDRO-4,4-DIMETHYL-2-OXAZOLYL)-1-METHYLETHYL]-BENZENEETHANOL Preparation Products And Raw materials
Preparation ProductsOxazole, 2-[1-[4-(2-chloroethyl)phenyl]-1-methylethyl]-4,5-dihydro-4,4-dimethyl-
2-(1-(4-(2-(4,4-dimethyl-4,5-dihydrooxazol-2-yl)propan- 2-yl)phenethyl)piperidin-4-yl)-1H-benzo[d]imidazole 2-Propenoic acid, 3-[3-[(phenylaMino)sulfonyl]phenyl]-, ethyl ester, (2E)- 4-FORMYLCINNAMIC ACID METHYL ESTER Bilastine 2-Propenoic acid, 3-[3-[(phenylaMino)sulfonyl]phenyl]-, Methyl ester, (2E)- 2-(2-(4-(2-(4-(1-(2-ethoxyethyl)-1H-benzo[d]imidazol-2-yl)piperidin-1-yl)ethyl)phenyl)propan-2-yl)-4,4-dimethyl-4,5-dihydrooxazole Benzeneethanol, 4-[1-(4,5-dihydro-4,4-dimethyl-2-oxazolyl)-1-methylethyl]-, 4-methylbenzenesulfonate (ester) 4-[1-(4,5-DIHYDRO-4,4-DIMETHYL-2-OXAZOLYL)-1-METHYLETHYL]-BENZENEETHANOL 2-BENZYL-4,4-DIMETHYL-4,5-DIHYDRO-1,3-OXAZOLE 2-ISOPROPYL-4,4-DIMETHYL-4,5-DIHYDRO-1,3-OXAZOLE 2-ETHYL-4,4-DIMETHYL-2-OXAZOLINE
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