ChemicalBook Product Catalog Biochemical Engineering Amino Acids and Derivatives Tyrosine derivatives N-ACETYL-L-TYROSINE ETHYL ESTER

N-ACETYL-L-TYROSINE ETHYL ESTER

N-ACETYL-L-TYROSINE ETHYL ESTER Basic information
Product Name:N-ACETYL-L-TYROSINE ETHYL ESTER
Synonyms:N-ALPHA-ACETYL-L-TYROSINE ETHYL ESTER;N-ACETYL-L-TYR ETHYL ESTER;N-ACETYL-L-TYROSINE ETHYL ESTER;ethyln-alpha-acetyl-tyrosinate;ATEE;ETHYLACETYL-L-TYROSINE;AC-TYR-OET;AC-TYROSINE-OET
CAS:840-97-1
MF:C13H17NO4
MW:251.28
EINECS:212-663-5
Product Categories:Amino Acid Ethyl Esters;Amino Acids (C-Protected);Amino Acids;Ac-Amino Acids;Amino Acids (N-Protected);Biochemistry
Mol File:840-97-1.mol
N-ACETYL-L-TYROSINE ETHYL ESTER Structure
N-ACETYL-L-TYROSINE ETHYL ESTER Chemical Properties
Melting point 78-81 °C
Boiling point 394.43°C (rough estimate)
density 1.1667 (rough estimate)
refractive index 22 ° (C=1, EtOH)
storage temp. Sealed in dry,2-8°C
pka9.75±0.15(Predicted)
Water Solubility 3.48g/L(28 ºC)
LogP0.592 (est)
CAS DataBase Reference840-97-1(CAS DataBase Reference)
EPA Substance Registry SystemL-Tyrosine, N-acetyl-, ethyl ester (840-97-1)
Safety Information
Safety Statements 24/25
WGK Germany 3
F 10-21
MSDS Information
ProviderLanguage
SigmaAldrich English
N-ACETYL-L-TYROSINE ETHYL ESTER Usage And Synthesis
DefinitionChEBI: Ethyl N-acetyl-L-tyrosinate is an L-tyrosine derivative that is the ethyl ester of N-acetyltyrosine. It is an ethyl ester, a member of acetamides, a member of phenols and a L-tyrosine derivative.
Enzyme inhibitorThis ester (FW = 251.28 g/mol; Abbreviation ATEE) is a substrate for chymotrypsin that is frequently used in assays of that enzyme. The reaction can be followed by observing the production of free carboxyl groups or by the decrease in absorbance at 237 nm and pH 7. Supersaturated stock solutions (i.e., 10-20 mM) can be prepared by dissolving ATEE in water at 85°C, followed by rapidly cooling to room temperature. These solutions are typically stable for six to twelve hours. N-Acetyl-L-tyrosine ethyl ester inhibits protein-disulfide reductase, glutathione-requiring; thiolsubtilisin; complement component C’.
N-ACETYL-L-TYROSINE ETHYL ESTER Preparation Products And Raw materials
Raw materialsN-Acetyl-L-tyrosine
Preparation ProductsLevothyroxine Sodium Impurity 16-->Ethyl L-tyrosinate-->AC-TYR-NHNH2
N-Acetyl-L-proline N-Acetyl-L-glutamine N-Acetyl-L-phenylalanine N-Acetyl-DL-methionine N-Acetyl-L-tryptophan N-Acetyl-L-cysteine N-乙酰-L-谷氨酸 AC-LYS-OH N-Acetyl-L-isoleucine N-Acetyl-L-methionine Ethyl L-tyrosinate L-Tyrosine Ethyl N-acetyl-L-tyrosinate hydrate Methyl L-tyrosinate N-Acetyl-L-tyrosine N-ACETYL-L-TYROSINE ETHYL ESTER MONOHYDRATE (ATEE) N-Acetyl-L-tyrosine Ethyl Ester, Monohydrate (1.00083)
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