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| | Hydrocortisone-17-butyrate Basic information |
| | Hydrocortisone-17-butyrate Chemical Properties |
| Melting point | 210.0 to 214.0 °C | | Boiling point | 466.2°C (rough estimate) | | density | 1.0914 (rough estimate) | | refractive index | 1.4593 (estimate) | | storage temp. | Refrigerator | | solubility | Chloroform (Slightly), Methanol (Slightly) | | form | neat | | pka | 12.98±0.10(Predicted) | | color | White to Off-White | | Merck | 14,4787 | | CAS DataBase Reference | 13609-67-1(CAS DataBase Reference) |
| WGK Germany | 2 | | RTECS | GM9002000 | | HS Code | 2937290000 |
| | Hydrocortisone-17-butyrate Usage And Synthesis |
| Uses | Hydrocortisone Butyrate is a topical corticosteroid use to treat a variety of dermatological conditions. It acts as an antiinflammatory, antiproliferative and immunosuppresive agent. | | Uses | antineoplastic | | Uses | Hydrocortisone-17-butyrate is a topical corticosteroid with anti-inflammatory properties; marker for topical corticosteroid allergy. | | Definition | ChEBI: Cortisol esterified with butyric acid at the 17-hydroxy group. | | Brand name | Locoid (Ferndale); Locoid (Yamanouchi). | | Biochem/physiol Actions | Hydrocortisone 17-butyrate is a corticosteroid that acts as a dermocorticoid due to its application in dermatological therapy. It exhibits therapeutic effects against vitiligo of the face and neck. | | Contact allergens | Hydrocortisone 17-butyrate is a C 17 ester of hydrocorti-
sone. It represents the D2 group of corticosteroids, non
C 16 methylated with a C 17 ester: hydrocortisone
17-butyrate, hydrocortisone 17-valerate, hydrocortisone
aceponate (17-propionate and 21-acetate), methylpred-
nisolone aceponate, and prednicarbate. It is sometimes
hydrolyzed in vivo into hydrocortisone, giving allergic
reactions to group-A-sensitized people. |
| | Hydrocortisone-17-butyrate Preparation Products And Raw materials |
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