5,6-DIHYDRO-2H-PYRAN-2-ONE

5,6-DIHYDRO-2H-PYRAN-2-ONE Basic information
Product Name:5,6-DIHYDRO-2H-PYRAN-2-ONE
Synonyms:2-Pentenoic acid, 5-hydroxy-, delta-lactone;5,6-Dihydro-2-pyranone;5,6-DIHYDRO-2H-PYRAN-2-ONE;Dihydropyranone;5,6-DIHYDRO-2H-PYRAN-2-ONE, TECH GRADE, 90%;5,6-Dihydro-2H-pyran-2-one technical grade, 90%;5,6-Dihydro-2H-pyran-2-one;2,5-dihydropyran-6-one
CAS:3393-45-1
MF:C5H6O2
MW:98.1
EINECS:628-075-0
Product Categories:Building Blocks;Chemical Synthesis;Building Blocks;Heterocyclic Building Blocks;Pyrans;Heterocyclic Building Blocks;API intermediates
Mol File:3393-45-1.mol
5,6-DIHYDRO-2H-PYRAN-2-ONE Structure
5,6-DIHYDRO-2H-PYRAN-2-ONE Chemical Properties
Boiling point 103 °C/10 mmHg (lit.)
density 1.139 g/mL at 25 °C (lit.)
refractive index n20/D 1.483(lit.)
Fp 115 °F
storage temp. 2-8°C
form clear liquid
color Colorless to Light orange to Yellow
Sensitive Moisture Sensitive
BRN 1610
InChIKeyQBDAFARLDLCWAT-UHFFFAOYSA-N
CAS DataBase Reference3393-45-1
Safety Information
Risk Statements 10
Safety Statements 23-24/25
RIDADR UN 1224 3/PG 3
WGK Germany 3
10-21
HazardClass 3
PackingGroup III
HS Code 2932209090
MSDS Information
ProviderLanguage
SigmaAldrich English
ALFA English
5,6-DIHYDRO-2H-PYRAN-2-ONE Usage And Synthesis
Uses5,6-Dihydro-2H-pyran-2-one has been used in the preparation of:
  • (1aR,5aR,5bS,6S,7S)-6,7-di-tert-butoxy-5-oxo-pyrrolidino[1,2-b]isoxazolidino[4,5-c]tetrahydropyran
  • 4-(phenyl)tetrahydro-2H-pyran-2-one
Synthesis Reference(s)The Journal of Organic Chemistry, 49, p. 1647, 1984 DOI: 10.1021/jo00183a030
Tetrahedron Letters, 25, p. 4783, 1984 DOI: 10.1016/S0040-4039(01)81518-5
General DescriptionEnantioselective conjugate addition of Grignard reagents to 5,6-dihydro-2H-pyran-2-one catalyzed by a chiral phosphine-copper iodide catalyst has been reported.
5,6-DIHYDRO-2H-PYRAN-2-ONE Preparation Products And Raw materials
Raw materials2H-Pyran-4(3H)-one-->3,4-Dihydro-2H-pyran
Preparation Products5-BROMO-2H-PYRAN-2-ONE,95%-->3-Bromo-2H-pyran-2-one
L-KAWAIN fuscin 5,6-DIHYDRO-2H-PYRAN-2-ONE Aflatoxin Fostriecin 6-heptyl-5,6-dihydro-2H-pyran-2-one AFLATOXIN G2 DIHYDROMETHYSTICIN RUBRATOXIN B BREVETOXIN PBTX-6 AFLATOXIN G1 5,6-DIHYDRO-4-HYDROXY-6-METHYL-2H-PYRAN-2-ONE BREVETOXIN PBTX-3 METHYSTICIN BREVETOXIN B NSC107662 TRANS-ACONITIC ACID ANHYDRIDE Kavain

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