2,5-DIDEOXY-2,5-IMINO-D-MANNITOL

2,5-DIDEOXY-2,5-IMINO-D-MANNITOL Basic information
Product Name:2,5-DIDEOXY-2,5-IMINO-D-MANNITOL
Synonyms:2R,5R-BIS(HYDROXYMETHYL)-3R,4R-DIHYDROXYPYRROLIDINE;2,5-DIDEOXY-2,5-IMINO-D-MANNITOL;DMDP;2,5-dihydroxymethyl-3,4-dihydroxypyrrolidine;(2R,5R)-bis(hydorxymethyl)-(3R,4R)-*dihydroxypyrr;(2R,5R)-BIS(HYDORXYMETHYL)-(3R,4R)-*DIHY DROXYPYRROL;2,5-Pyrrolidinedimethanol, 3,4-dihydroxy-, (2R,3R,4R,5R)-;(2R,5R)-BIS(HYDORXYMETHYL)-(3R,4R)- DIHYDROXYPYRROLIDINE
CAS:59920-31-9
MF:C6H13NO4
MW:163.17
EINECS:633-130-7
Product Categories:Carbohydrates & Derivatives;All Inhibitors;Glycosidase Inhibitors;Inhibitors;Imidazoles, Pyrroles, Pyrazoles, Pyrrolidines
Mol File:59920-31-9.mol
2,5-DIDEOXY-2,5-IMINO-D-MANNITOL Structure
2,5-DIDEOXY-2,5-IMINO-D-MANNITOL Chemical Properties
Melting point 101-103°C
Boiling point 395.9±37.0 °C(Predicted)
density 1.408±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility Methanol (Slightly), Water (Slightly)
pka13.67±0.70(Predicted)
form Solid
color Off-White to Pale Yellow
Stability:Hygroscopic
CAS DataBase Reference59920-31-9
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36
WGK Germany 3
HS Code 29400090
MSDS Information
ProviderLanguage
SigmaAldrich English
2,5-DIDEOXY-2,5-IMINO-D-MANNITOL Usage And Synthesis
Chemical PropertiesOff-White Solid
UsesMany pyrrolidines are powerful inhibitors of glycohydrolases, enzymes responsible for cleavage of glycosidic bonds, glycoprotein processing and the gastrointestinal breakdown of dietary carbohydrates. These compounds are charged at physiological pH and are believed to associate with acidic amino acids at the active site. Inhibition of glycohydrolases could be of therapeutic value for the treatment of viral infections, cancer, diabetes, and obesity.
UsesA glucosidase inhibitor.
DefinitionChEBI: 2,5-bis(hydroxymethyl)-3,4-dihydroxypyrrolidine is a dihydroxypyrrolidine.
2,5-DIDEOXY-2,5-IMINO-D-MANNITOL Preparation Products And Raw materials
Clodronate disodium 2,5-DIDEOXY-2,5-IMINO-D-MANNITOL 1,5-DIDEOXY-1,5-IMINO-D-MANNITOL, HCL,1,5-DIDEOXY-1,5-IMINO-D-MANNITOL HYDROCHLORIDE 1,4-Dideoxy-1,4-imino-D-mannitol AUSTRALINE HYDROCHLORIDE 1,5-Dideoxy-1,5-imino-D-mannitol BETA-GLUCOSIDASE 4-DIDEOXY-1,4-IMINO-D-MANNITOL HCL AUSTRALINE trans-3,4-Dihydroxypyrrolidine 1,4-DIDEOXY-1,4-IMINO-D-MANNITOL HYDROCHLORIDE 2,5-Dideoxy-2,5-imino-D-mannitolHCl (S)-3-Hydroxypyrrolidine 2,5-DIDEOXY-2,5-IMINO-D-MANNITOL HCL DMDP-TAT-59 Pyrrolidine

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