METHOXYCARBONYLSULFENYL CHLORIDE

METHOXYCARBONYLSULFENYL CHLORIDE Basic information
Product Name:METHOXYCARBONYLSULFENYL CHLORIDE
Synonyms:METHOXYCARBONYLSULFENYL CHLORIDE;METHOXYCARBONYLSULPHENYL CHLORIDE;5-CHLORO O-METHYL THIOCARBONATE;thiocarbonic acid, anhydrosulphide with methyl thiohypochlorite;Methoxycarbonylsulfenylchloride,95%;(Chlorosulfanyl)(methoxy)oxomethane;Carbonothioic acid, anhydrosulfide with thiohypochlorous acid, methyl ester;S-CHLORO O-METHYL THIOCARBONATE
CAS:26555-40-8
MF:C2H3ClO2S
MW:126.56
EINECS:247-801-3
Product Categories:Protection & Derivatization Reagents (for Synthesis);Sulfur Compounds (for Synthesis);Synthetic Organic Chemistry
Mol File:26555-40-8.mol
METHOXYCARBONYLSULFENYL CHLORIDE Structure
METHOXYCARBONYLSULFENYL CHLORIDE Chemical Properties
Boiling point 133-134 °C(lit.)
density 1.399 g/mL at 25 °C(lit.)
refractive index n20/D 1.481(lit.)
Fp 130 °F
storage temp. 2-8°C
solubility Miscible with dichlormethane.
form Liquid
Specific Gravity1.399
color Clear bright yellow
Sensitive Moisture Sensitive
BRN 1849908
InChIKeyTXJXPZVVSLAQOQ-UHFFFAOYSA-N
CAS DataBase Reference26555-40-8(CAS DataBase Reference)
Safety Information
Hazard Codes C
Risk Statements 10-34
Safety Statements 26-36/37/39-45
RIDADR UN 2920 8/PG 2
WGK Germany 3
10-21
HazardClass 8
PackingGroup II
HS Code 29309099
MSDS Information
ProviderLanguage
ACROS English
SigmaAldrich English
ALFA English
METHOXYCARBONYLSULFENYL CHLORIDE Usage And Synthesis
Chemical PropertiesCLEAR BRIGHT YELLOW LIQUID
UsesMethoxycarbonylsulfenyl chloride may be used to prepare 3-[(methoxycarbonyl)dithio]-L-alanine, via reaction with L-cysteine. It is suitable for use in the synthesis of 3-2 pyridinyldithio propanoic acid hydrazide (PDPH), an important heterobifunctional crosslinker widely used in bioconjugate techniques for making macromolecule-drug conjugates.
UsesMethoxycarbonylsulfenyl chloride is used to prepare 3-[(methoxycarbonyl)dithio]-L-alanine by reacting with L-cysteine. Further, it is used in the synthesis of 3-2 pyridinyldithio propanoic acid hydrazide (PDPH). It serves as an important heterobifunctional crosslinker, which is a crosslinker used to make macromolecule-drug conjugates.
General DescriptionMethoxycarbonylsulfenyl chloride is a sulfenyl carbonyl compound. Photoinduced fragmentations of methoxycarbonylsulfenyl chloride is investigated in the gaseous phase by using synchrotron radiation and multicoincidence techniques. The molecular structure and conformational properties of methoxycarbonylsulfenyl chloride is studied in the gas and solid phases by gas electron diffraction, low-temperature X-ray diffraction and vibrational spectroscopy. The anomeric and mesomeric effects in methoxycarbonylsulfenyl chloride is reported.
METHOXYCARBONYLSULFENYL CHLORIDE Preparation Products And Raw materials
Preparation Products3-(Pridin-2-yldisulfanyl)propan-1-ol
Nickel chloride Bismuth trichloride Lanthanum(III) chloride Calcium chloride Sodium chloride Allylpalladium(II) Chloride Dimer Lithium chloride monohydrate Zinc chloride CERIUM(III) CHLORIDE HEPTAHYDRATE Choline chloride Palladium chloride Potassium chloride Di-chlorobis[(1,2,3-)-1-phenyl-2-propenyl]dipalladium(II) Lithium chloride Magnesium chloride METHOXYCARBONYLSULFENYL CHLORIDE CARBONYL SULFIDE

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